piRNA Rules of Engagement

被引：11
作者：
Svendsen, Joshua M. [1 ,2 ]
Montgomery, Taiowa A. [1 ]
机构：
[1] Colorado State Univ, Dept Biol, Ft Collins, CO 80523 USA
[2] Colorado State Univ, Cell & Mol Biol Program, Ft Collins, CO 80523 USA
来源：
DEVELOPMENTAL CELL | 2018年 / 44卷 / 06期
关键词：
C; ELEGANS; GERMLINE; RNA;
D O I：
10.1016/j.devcel.2018.03.006
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
piRNAs are known to silence transposable elements, but not all piRNAs match transposon sequences. Recent studies from Shen et al. (2018) and Zhang et al. (2018) identify rules for piRNA target recognition in Caenorhabditis elegans. Permissive pairing rules allow targeting of essentially all germline mRNAs, while protective mechanisms prevent silencing self-genes.
引用
收藏
页码：657 / 658
页数：2
相关论文
共 10 条
  • [1] MicroRNAs: Target Recognition and Regulatory Functions
    Bartel, David P.
    [J]. CELL, 2009, 136 (02) : 215 - 233
  • [2] An Abundant Class of Non-coding DNA Can Prevent Stochastic Gene Silencing in the C. elegans Germline
    Frokjaer-Jensen, Christian
    Jain, Nimit
    Hansen, Loren
    Davis, M. Wayne
    Li, Yongbin
    Zhao, Di
    Rebora, Karine
    Millet, Jonathan R. M.
    Liu, Xiao
    Kim, Stuart K.
    Dupuy, Denis
    Jorgensen, Erik M.
    Fire, Andrew Z.
    [J]. CELL, 2016, 166 (02) : 343 - 357
  • [3] Pachytene piRNAs instruct massive mRNA elimination during late spermiogenesis
    Gou, Lan-Tao
    Dai, Peng
    Yang, Jian-Hua
    Xue, Yuanchao
    Hu, Yun-Ping
    Zhou, Yu
    Kang, Jun-Yan
    Wang, Xin
    Li, Hairi
    Hua, Min-Min
    Zhao, Shuang
    Hu, Si-Da
    Wu, Li-Gang
    Shi, Hui-Juan
    Li, Yong
    Fu, Xiang-Dong
    Qu, Liang-Hu
    Wang, En-Duo
    Liu, Mo-Fang
    [J]. CELL RESEARCH, 2014, 24 (06) : 680 - 700
  • [4] PIWI-Interacting RNA: Its Biogenesis and Functions
    Iwasaki, Yuka W.
    Siomi, Mikiko C.
    Siomi, Haruhiko
    [J]. ANNUAL REVIEW OF BIOCHEMISTRY, VOL 84, 2015, 84 : 405 - 433
  • [5] A Neuronal piRNA Pathway Inhibits Axon Regeneration in &ITC&IT. &ITelegans&IT
    Kim, Kyung Won
    Tang, Ngang Heok
    Andrusiak, Matthew G.
    Wu, Zilu
    Chisholm, Andrew D.
    Jin, Yishi
    [J]. NEURON, 2018, 97 (03) : 511 - +
  • [6] C. elegans piRNAs Mediate the Genome-wide Surveillance of Germline Transcripts
    Lee, Heng-Chi
    Gu, Weifeng
    Shirayama, Masaki
    Youngman, Elaine
    Conte, Darryl, Jr.
    Mello, Craig C.
    [J]. CELL, 2012, 150 (01) : 78 - 87
  • [7] The Coding Regions of Germline mRNAs Confer Sensitivity to Argonaute Regulation in C. elegans
    Seth, Meetu
    Shirayama, Masaki
    Tang, Wen
    Shen, En-Zhi
    Tu, Shikui
    Lee, Heng-Chi
    Weng, Zhiping
    Mello, Craig C.
    [J]. CELL REPORTS, 2018, 22 (09): : 2254 - 2264
  • [8] Identification of piRNA Binding Sites Reveals the Argonaute Regulatory Landscape of the C-elegans Germline
    Shen, En-Zhi
    Chen, Hao
    Ozturk, Ahmet R.
    Tu, Shikui
    Shirayama, Masaki
    Tang, Wen
    Ding, Yue-He
    Dai, Si-Yuan
    Weng, Zhiping
    Mello, Craig C.
    [J]. CELL, 2018, 172 (05) : 937 - +
  • [9] A Sex Chromosome piRNA Promotes Robust Dosage Compensation and Sex Determination in C. elegans
    Tang, Wen
    Seth, Meetu
    Tu, Shikui
    Shen, En-Zhi
    Li, Qian
    Shirayama, Masaki
    Weng, Zhiping
    Mello, Craig C.
    [J]. DEVELOPMENTAL CELL, 2018, 44 (06) : 762 - +
  • [10] The piRNA targeting rules and the resistance to piRNA silencing in endogenous genes
    Zhang, Donglei
    Tu, Shikui
    Stubna, Michael
    Wu, Wei-Sheng
    Huang, Wei-Che
    Weng, Zhiping
    Lee, Heng-Chi
    [J]. SCIENCE, 2018, 359 (6375) : 587 - 591
1