Testosterone replacement therapy and voiding dysfunction

被引：21
作者：
Baas, Wesley [1 ]
Koehler, Tobias S. [1 ]
机构：
[1] Southern Illinois Univ, Sch Med, Div Urol, Springfield, IL 62702 USA
来源：
TRANSLATIONAL ANDROLOGY AND UROLOGY | 2016年 / 5卷 / 06期
关键词：
Benign prostatic hyperplasia (BPH); lower urinary tract symptoms (LUTS); testosterone replacement therapy (TRT); hypogonadism; BENIGN PROSTATIC HYPERPLASIA; LOWER URINARY-TRACT; QUALITY-OF-LIFE; LATE-ONSET HYPOGONADISM; RANDOMIZED CONTROLLED-TRIAL; HEALTHY-YOUNG MEN; OLDER MEN; ERECTILE DYSFUNCTION; SERUM TESTOSTERONE; METABOLIC SYNDROME;
D O I：
10.21037/tau.2016.08.11
中图分类号：
R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
摘要：
Testosterone replacement therapy (TRT) represents an increasing popular treatment option for men with late-onset hypogonadism (LOH). Because of unsubstantiated beliefs of testosterone's effect on the prostate, the FDA has recently placed a warning on testosterone products, stating that TRT may worsen benign prostatic hyperplasia (BPH). Within this review article we have demonstrated the current understanding of the physiology of testosterone and its relationship with prostatic and lower urinary tract physiology. The current evidence suggests that not only does TRT not worsen lower urinary tract symptoms (LUTS), but that hypogonadism itself is an important risk factor for LUTS/BPH.
引用
收藏
页码：890 / 897
页数：8
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