Quantitative analysis of morphine and noscapine using corona discharge ion mobility spectrometry with ammonia reagent gas

被引:60
作者
Khayamian, T. [1 ]
Tabrizchi, M. [1 ]
Jafari, M. T. [1 ]
机构
[1] Isfahan Univ Technol, Dept Chem, Esfahan 84154, Iran
关键词
corona discharge; narcotics; ion mobility spectrometry;
D O I
10.1016/j.talanta.2005.11.016
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Morphine and noscapine were determined using corona discharge ion mobility spectrometry. The detection limits were 5.6 x 10(-11) and 6.7 x 10(-11) g for morphine and noscapine, respectively. The linear dynamic ranges of the calibration plots for the compounds were about three orders of magnitude. The method has also been successfully applied for simultaneous determination of the compounds using the standard addition method. (c) 2005 Elsevier B.V. All rights reserved.
引用
收藏
页码:795 / 799
页数:5
相关论文
共 24 条
[1]  
Chen YP, 1999, J FOOD DRUG ANAL, V7, P13
[2]   Simultaneous determination of in total 17 opium alkaloids and opioids in blood and urine by fast liquid chromatography-diode-array detection-fluorescence detection, after solid-phase extraction [J].
Dams, R ;
Benijts, T ;
Lambert, WE ;
De Leenheer, AP .
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2002, 773 (01) :53-61
[3]  
Eiceman G.A., 1993, ION MOBILITY SPECTRO
[4]  
FOSTER S, 1972, ENCY IND CHEM ANAL, V16, P258
[5]   Tris(2,2-bipyridyl)ruthenium (II) chemiluminescence in a microflow injection system for codeine determination [J].
Greenway, GM ;
Nelstrop, LJ ;
Port, SN .
ANALYTICA CHIMICA ACTA, 2000, 405 (1-2) :43-50
[6]   Simple and highly sensitive determination of morphine in rat plasma by liquid chromatography with fluorescence detection [J].
Hara, S ;
Mochinaga, S ;
Fukuzawa, M ;
Ono, N ;
Kuroda, T .
ANALYTICA CHIMICA ACTA, 1999, 387 (02) :121-126
[7]   Simultaneous determination of codeine and it seven metabolites in plasma and urine by high-performance liquid chromatography with ultraviolet and electrochemical detection [J].
He, HB ;
Shay, SD ;
Caraco, Y ;
Wood, M ;
Wood, AJJ .
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1998, 708 (1-2) :185-193
[8]   Highly sensitive gas chromatographic-tandem mass spectrometric method for the determination of morphine and codeine in serum and urine in the femtomolar range [J].
Hofmann, U ;
Seefried, S ;
Schweizer, E ;
Ebner, T ;
Mikus, G ;
Eichelbaum, M .
JOURNAL OF CHROMATOGRAPHY B, 1999, 727 (1-2) :81-88
[9]   Analysis of 2,4,6-trinitrotoluene, pentaerythritol tetranitrate and cyclo-1,3,5-trimethylene-2,4,6-trinitramine using negative corona discharge ion mobility spectrometry [J].
Khayamian, T ;
Tabrizchi, M ;
Jafari, MT .
TALANTA, 2003, 59 (02) :327-333
[10]   Direct determination of ultra-trace amounts of acetone by corona-discharge ion mobility spectrometry [J].
Khayamian, T ;
Tabrizchi, M ;
Taj, N .
FRESENIUS JOURNAL OF ANALYTICAL CHEMISTRY, 2001, 370 (08) :1114-1116