Photoacoustic imaging based on MEMS mirror scanning

被引:47
作者
Xi, Lei [1 ]
Sun, Jingjing [2 ]
Zhu, Yiping [2 ]
Wu, Lei [2 ]
Xie, Huikai [2 ]
Jiang, Huabei [1 ]
机构
[1] Univ Florida, Dept Biomed Engn, Gainesville, FL 32611 USA
[2] Univ Florida, Dept Elect & Comp Engn, Gainesville, FL 32611 USA
关键词
D O I
10.1364/BOE.1.001278
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
A microelectromechanical systems (MEMS)-based photoacoustic imaging system is reported for the first time. In this system, the MEMS-based light scanning subsystem and a ring-shaped polyvinylidene fluoride (PVDF) transducer are integrated into a miniaturized probe that is capable of three-dimensional (3D) photoacoustic imaging. It is demonstrated that the imaging system is able to image small objects embedded in phantom materials and in chicken and to in vivo visualize blood vessels under the skin of a human hand. (C) 2010 Optical Society of America
引用
收藏
页码:1278 / 1283
页数:6
相关论文
共 17 条
[1]   Two-axis MEMS scanning catheter for ultrahigh resolution three-dimensional and en face imaging [J].
Aguirre, Aaron D. ;
Herz, Paul R. ;
Chen, Yu ;
Fujimoto, James G. ;
Piyawattanametha, Wibool ;
Fan, Li ;
Wu, Ming C. .
OPTICS EXPRESS, 2007, 15 (05) :2445-2453
[2]   Photoacoustic mammography laboratory prototype: imaging of breast tissue phantoms [J].
Manohar, S ;
Kharine, A ;
van Hespen, JCG ;
Steenbergen, W ;
van Leeuwen, TG .
JOURNAL OF BIOMEDICAL OPTICS, 2004, 9 (06) :1172-1181
[3]   The Twente Photoacoustic Mammoscope: system overview and performance [J].
Manohar, S ;
Kharine, A ;
van Hespen, JCG ;
Steenbergen, W ;
van Leeuwen, TG .
PHYSICS IN MEDICINE AND BIOLOGY, 2005, 50 (11) :2543-2557
[4]  
Oraevsky A. A., 2003, BIOMEDICAL PHOTONICS, VPM125, p34/1
[5]  
ORAEVSKY AA, 1994, P SOC PHOTO-OPT INS, V2134, P122
[6]   Laser optoacoustic imaging of breast cancer in vivo [J].
Oraevsky, AA ;
Karabutov, AA ;
Solomatin, SV ;
Savateeva, EV ;
Andreev, VG ;
Gatalica, Z ;
Singh, H ;
Fleming, RD .
BIOMEDICAL OPTOACOUSTICS II, 2001, 4256 :6-15
[7]   3D In Vivo optical coherence tomography based on a low-voltage, large-scan-range 2D MEMS mirror [J].
Sun, Jingjing ;
Guo, Shuguang ;
Wu, Lei ;
Liu, Lin ;
Choe, Se-Woon ;
Sorg, Brian S. ;
Xie, Huikai .
OPTICS EXPRESS, 2010, 18 (12) :12065-12075
[8]   Quantitative three-dimensional photoacoustic tomography of the finger joints: an in vivo study [J].
Sun, Yao ;
Sobel, Eric ;
Jiang, Huabei .
JOURNAL OF BIOMEDICAL OPTICS, 2009, 14 (06)
[9]   Quantitative three-dimensional photoacoustic tomography of the finger joints: phantom studies in a spherical scanning geometry [J].
Sun, Yao ;
Jiang, Huabei .
PHYSICS IN MEDICINE AND BIOLOGY, 2009, 54 (18) :5457-5467
[10]   In vivo endoscopic optical coherence tomography by use of a rotational microelectromechanical system probe [J].
Tran, PH ;
Mukai, DS ;
Brenner, M ;
Chen, ZP .
OPTICS LETTERS, 2004, 29 (11) :1236-1238