Inducible expression of bcl-2 antisense RNA promotes apoptosis of human gastric cancer cell line

被引：0
作者：
Zhang, J
Peng, WD
Hui, HX
Jin, M
Wang, DN
Wang, CJ
Qian, HW
机构：
[1] Acad Mil Med Sci, Inst Radiat Med, Beijing 100850, Peoples R China
[2] Forth Mil Med Univ, Dept Biochem & Mol Biol, Xian 710033, Peoples R China
[3] Forth Mil Med Univ, Dept Chem, Xian 710033, Peoples R China
来源：
ACTA BIOCHIMICA ET BIOPHYSICA SINICA | 1999年 / 31卷 / 03期
关键词：
antisense; bcl-2; apoptosis; gene therapy;
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A lot of molecular biological techniques was used to observe the effect of bcl-2 antisence RNA on human gastric cancer cell line SGC7901 and to detect the inducibility and promotion of MT-II promoter. The results showed that MT-II promoter could be activated by the induction with 160 mu mol/L Zn2+ and the expression of Bcl-2 plays an important role in apoptosis of SGC7901 cells.
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页码：279 / 283
页数：5
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