Synthesis, characterization and biological studies of novel imines and azetidinones derivatives of haloaryloxy moiety

被引：0

作者：

Fuloria, Neeraj Kumar ^{[1
]}

Singh, Vijender ^{[1
]}

Shaharyar, Mohd. ^{[2
]}

Ali, Mohd. ^{[2
]}

机构：

[1] Rameesh Inst Vocat & Tech Educ, Dept Pharm, Greater Noida 201306, India

[2] Jamia Hamdard, Fac Pharm, Dept Pharmaceut Chem & Pharmacognosy, New Delhi 110062, India

来源：

ASIAN JOURNAL OF CHEMISTRY | 2008年 / 20卷 / 06期

关键词：

azetidinones; imines; hydrazine; haloaryloxy moiety; antibacterial activity; antifungal activity;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Haloaryloxy moiety on refluxing with chloroethyl acetate in the presence of potassium carbonate and acetone yielded ethyl halolaryloxy acetate (1), which was reacted with hydrazine hydrate to produce haloaryloxyacetyl hydrazine (2), which on treatment with aromatic aldehydes yields imines (3A-J) and subsequently into azetidinones (4A-J). The novel series of compounds were elucidated on the basis of spectral studies and screened for antibacterial and antifungal studies.

引用

页码：4891 / 4900

页数：10

共 10 条

[1] MONOCYCLIC ANTIBIOTIC BETA-LACTAMS [J].

ABDULLA, RF ;

FUHR, KH .

JOURNAL OF MEDICINAL CHEMISTRY, 1975, 18 (06) :625-627

[2]

AGARWAL R, 1989, INDIAN J CHEM B, V28, P893

[3]

Choudhari BP, 2003, INDIAN J HETEROCY CH, V12, P197

[4]

DOHERTY JB, 1992, Patent No. 966850

[5]

Govindarajan R, 2003, INDIAN J HETEROCY CH, V12, P229

[6]

Havaldar FH, 2004, INDIAN J HETEROCY CH, V13, P197

[7]

Mulwad VV, 2002, INDIAN J HETEROCY CH, V11, P291

[8]

Oza HB, 2003, INDIAN J HETEROCY CH, V12, P275

[9]

SHINGARE MS, 1976, J INDIAN CHEM SOC, V53, P1036

[10]

VASHI BS, 1995, INDIAN J CHEM B, V34, P802

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