Anti-hyperglycemic potential of natural products

被引：74

作者：

Matsui, T ^{[1
]}

Ogunwande, IA ^{[1
]}

Abesundara, KJM ^{[1
]}

Matsumoto, K ^{[1
]}

机构：

[1] Kyushu Univ, Div Food Biotechnol, Dept Biosci Biotechnol, Fac Agr,Grad Sch,Higashi Ku, Fukuoka 8128581, Japan

来源：

MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2006年 / 6卷 / 03期

关键词：

diabetes; alpha-glucosidase; maltase inhibition; anti-hyperglycemic effect;

D O I：

10.2174/138955706776073484

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

In order to evaluate the anti-hyperglycemic effect of natural compounds via the inhibition of alpha-glucosidase (AGH), the potential inhibitory effect of anthocyanins, caffeic acid analogs, and caffeoylquinic acid analogs have been reviewed. A new AGH assay system to mimic the membrane-bound AGH at the small intestine was proposed and evaluated.

引用

页码：349 / 356

页数：8

共 41 条

[1] α-glucosidase inhibitory activity of some Sri Lanka plant extracts, one of which, Cassia auriculata, exerts a strong anti hyperglycemic effect in rats comparable to the therapeutic drug acarbose [J].