Hydatidiform moles and gestational trophoblastic neoplasia

被引:1
作者
Golfier, F. [1 ,2 ,3 ,4 ]
Guastalla, J. -P. [1 ,7 ]
Trillet-Lenoir, V. [1 ,2 ,5 ]
Massardier, J. [1 ,3 ]
Pavic, M. [7 ]
Schott, A. M. [1 ,2 ,6 ]
Raudrant, D. [1 ,2 ,3 ,4 ]
机构
[1] Hosp Civils Lyon, Hotel Dieu, Ctr Reference Malad Trophoblast, F-69002 Lyon, France
[2] Univ Lyon, F-69622 Villeurbanne, France
[3] Hosp Civils Lyon, Hotel Dieu, Serv Gynecol Obstet, F-69002 Lyon, France
[4] Ctr Hosp Lyon Sud, Serv Chirurg Gynecol & Cancerol, F-69002 Lyon, France
[5] Ctr Hosp Lyon Sud, Med Oncol Serv, F-69002 Lyon, France
[6] Ctr Hosp Lyon Sud, Dept Informat Med & Cancerol & Cellule Appui Epid, F-69002 Lyon, France
[7] Ctr Leon Berard, Med Oncol Serv, F-69003 Lyon, France
关键词
Gestational trophoblastic neoplasia; Hydatidiform mole; Reference centre;
D O I
10.1007/s10269-008-0974-4
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Partial and complete hydatidiform moles can secondarily turn to gestational trophoblastic neoplasia (GTN). Diagnosis of GTN is made when hCG does not return to normal value after a molar pregnancy or when histology findings show a choriocarcinoma. A check-up for metastasis allows calculating the FIGO score that differentiates low risk patients treated with methotrexate from high risk patients treated with polychemotherapy. The French trophoblastic disease reference centre has been implemented as an entity within a network organised between Lyon, Tours, Paris and Marseille; this network aims to register patients and optimize the treatment of GTN patients in France.
引用
收藏
页码:604 / 611
页数:8
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