Immunoproteasomes Are Important for Proteostasis in Immune Responses

被引：41

作者：

Ebstein, Frederic ^{[1
]}

Voigt, Antje ^{[1
,2
]}

Lange, Nicole ^{[1
]}

Warnatsch, Annika ^{[1
]}

Schroeter, Friederike ^{[3
]}

Prozorovski, Timour ^{[3
]}

Kuckelkorn, Ulrike ^{[1
]}

Aktas, Orhan ^{[3
]}

Seifert, Ulrike ^{[4
]}

Kloetzel, Peter-M. ^{[1
]}

Krueger, Elke ^{[1
]}

机构：

[1] Charite, Inst Biochem CCM, Charite CrossOver, D-10117 Berlin, Germany

[2] DZHK German Ctr Cardiovasc Res, D-10117 Berlin, Germany

[3] Univ Dusseldorf, Fac Med, Dept Neurol, D-40225 Dusseldorf, Germany

[4] Otto von Guericke Univ, Fac Med, Inst Mol & Clin Immunol, D-39120 Magdeburg, Germany

来源：

CELL | 2013年 / 152卷 / 05期

关键词：

PROTEASOME SUBUNIT; LIPODYSTROPHY; MUTATION;

D O I：

10.1016/j.cell.2013.02.018

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：935 / 937

页数：3

共 12 条

[1] PSMB8 Encoding the β5i Proteasome Subunit Is Mutated in Joint Contractures, Muscle Atrophy, Microcytic Anemia, and Panniculitis-Induced Lipodystrophy Syndrome [J].

Agarwal, Anil K. ;

Xing, Chao ;

DeMartino, George N. ;

Mizrachi, Dario ;

Dolores Hernandez, Maria ;

Sousa, Ana Berta ;

Martinez de Villarreal, Laura ;

dos Santos, Heloisa G. ;

Garg, Abhimanyu .

AMERICAN JOURNAL OF HUMAN GENETICS, 2010, 87 (06) :866-872

[2] Proteasome assembly defect due to a proteasome subunit beta type 8 (PSMB8) mutation causes the autoinflammatory disorder, Nakajo-Nishimura syndrome [J].

Arima, Kazuhiko ;

Kinoshita, Akira ;

Mishima, Hiroyuki ;

Kanazawa, Nobuo ;

Kaneko, Takeumi ;

Mizushima, Tsunehiro ;

Ichinose, Kunihiro ;

Nakamura, Hideki ;

Tsujino, Akira ;

Kawakami, Atsushi ;

Matsunaka, Masahiro ;

Kasagi, Shimpei ;

Kawano, Seiji ;

Kumagai, Shunichi ;

Ohmura, Koichiro ;

Mimori, Tsuneyo ;

Hirano, Makito ;

Ueno, Satoshi ;

Tanaka, Keiko ;

Tanaka, Masami ;

Toyoshima, Itaru ;

Sugino, Hirotoshi ;

Yamakawa, Akio ;

Tanaka, Keiji ;

Niikawa, Norio ;

Furukawa, Fukumi ;

Murata, Shigeo ;

Eguchi, Katsumi ;

Ida, Hiroaki ;

Yoshiura, Koh-ichiro .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (36) :14914-14919

[3] Ubiquitin conjugase UBCH8 targets active FMS-like tyrosine kinase 3 for proteasomal degradation [J].

Buchwald, M. ;

Pietschmann, K. ;

Mueller, J. P. ;

Boehmer, F. D. ;

Heinzel, T. ;

Kraemer, O. H. .

LEUKEMIA, 2010, 24 (08) :1412-1421

[4] Rates of processing determine the immunogenicity of immunoproteasome-generated epitopes [J].

Deol, Parampal ;

Zaiss, Dietmar M. W. ;

Monaco, John J. ;

Sijts, Alice J. A. M. .

JOURNAL OF IMMUNOLOGY, 2007, 178 (12) :7557-7562

[5] Immuno- and Constitutive Proteasome Crystal Structures Reveal Differences in Substrate and Inhibitor Specificity [J].

Huber, Eva M. ;

Basler, Michael ;

Schwab, Ricarda ;

Heinemeyer, Wolfgang ;

Kirk, Christopher J. ;

Groettrup, Marcus ;

Groll, Michael .

CELL, 2012, 148 (04) :727-738

[6] A Novel Role for the Immunoproteasome in Retinal Function [J].

Hussong, Stacy A. ;

Roehrich, Heidi ;

Kapphahn, Rebecca J. ;

Maldonado, Marcela ;

Pardue, Machelle T. ;

Ferrington, Deborah A. .

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2011, 52 (02) :714-723

[7] A mutation in the immunoproteasome subunit PSMB8 causes autoinflammation and lipodystrophy in humans [J].

Kitamura, Akiko ;

Maekawa, Yoichi ;

Uehara, Hisanori ;

Izumi, Keisuke ;

Kawachi, Izumi ;

Nishizawa, Masatoyo ;

Toyoshima, Yasuko ;

Takahashi, Hitoshi ;

Standley, Daron M. ;

Tanaka, Keiji ;

Hamazaki, Jun ;

Murata, Shigeo ;

Obara, Koji ;

Toyoshima, Itaru ;

Yasutomo, Koji .

JOURNAL OF CLINICAL INVESTIGATION, 2011, 121 (10) :4150-4160

[8] Mutations in proteasome subunit ß type 8 cause chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature with evidence of genetic and phenotypic heterogeneity [J].

Liu, Yin ;

Ramot, Yuval ;

Torrelo, Antonio ;

Paller, Amy S. ;

Si, Nuo ;

Babay, Sofia ;

Kim, Peter W. ;

Sheikh, Afzal ;

Lee, Chyi-Chia Richard ;

Chen, Yongqing ;

Vera, Angel ;

Zhang, Xue ;

Goldbach-Mansky, Raphaela ;

Zlotogorski, Abraham .

ARTHRITIS AND RHEUMATISM, 2012, 64 (03) :895-907

[9] Immuno- and Constitutive Proteasomes Do Not Differ in Their Abilities to Degrade Ubiquitinated Proteins [J].

Nathan, James A. ;

Spinnenhim, Valentina ;

Schmidtke, Gunter ;

Basler, Michael ;

Groettrup, Marcus ;

Goldberg, Alfred L. .

CELL, 2013, 152 (05) :1184-1194

[10] Impairment of Immunoproteasome Function by β5i/LMP7 Subunit Deficiency Results in Severe Enterovirus Myocarditis [J].

Opitz, Elisa ;

Koch, Annett ;

Klingel, Karin ;

Schmidt, Frank ;

Prokop, Stefan ;

Rahnefeld, Anna ;

Sauter, Martina ;

Heppner, Frank L. ;

Voelker, Uwe ;

Kandolf, Reinhard ;

Kuckelkorn, Ulrike ;

Stangl, Karl ;

Krueger, Elke ;

Kloetzel, Peter M. ;

Voigt, Antje .

PLOS PATHOGENS, 2011, 7 (09)

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