Inquiry learning, which creates a similar situation and way of scientific research in the teaching process, lets the students learn to collect, analyze and judge of lots information, through active explore, discover and experience, thus to promote the ability of thinking and creativity. This paper analyses and discusses content organization, plan design and assessment method of implementation plan of inquiry learning based on the course and problems, and combining with the practical teaching process, the scheme implementation is applied. Practice shows that the scheme is feasible and effective to improve students' enthusiasm of active learning, and exercise the students' ability of analyzing and solving problems.