Regioselective Cleavage of Unstrained C-C Bond and C-H Bond: Palladium-Copper Catalyzed Deacetophenonylative Arylation of Coumarin Derivatives

被引：7

作者：

Sun, Manman ^{[1
]}

Shen, Guodong ^{[1
]}

Bao, Weiliang ^{[1
]}

机构：

[1] Zhejiang Univ, Dept Chem, Hangzhou 310028, Peoples R China

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2012年 / 354卷 / 18期

关键词：

C?C bond cleavage; copper; coumarins; palladium; 2-ARYLACETIC ACID-ESTERS; CARBON-CARBON BONDS; LEWIS-ACID; ACTIVATION; KETONES; ALKENES; CYCLOBUTANONES; ARYLMETHANOLS; CYCLOADDITION; ACETOACETATE;

D O I：

10.1002/adsc.201200539

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A Ca?C beta bond activation of the carbonyl group in unstrained ketones catalyzed cooperatively by palladium and copper(II) with the departure of the acetophenone has been developed, and the subsequent coupling with a variety of aromatics via the formal C?H activation similar to the FriedelCrafts reaction affords the skeleton-reconstructed coumarin derivatives with high regioselectivity.

引用

页码：3468 / 3474

页数：7

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