Epidemiology of preeclampsia: impact of obesity

被引：272

作者：

Jeyabalan, Arun ^{[1
]}

机构：

[1] Univ Pittsburgh, Sch Med, Dept Obstet Gynecol & Reprod Sci, Pittsburgh, PA USA

来源：

NUTRITION REVIEWS | 2013年 / 71卷

基金：

美国国家卫生研究院;

关键词：

obesity; preeclampsia; pregnancy; ADVERSE NEONATAL OUTCOMES; LONG-TERM MORTALITY; BODY-MASS INDEX; RISK-FACTORS; HYPERTENSIVE DISORDERS; ASYMMETRIC DIMETHYLARGININE; PREGNANCY COMPLICATIONS; ANGIOGENIC FACTORS; CIGARETTE-SMOKING; NULLIPAROUS WOMEN;

D O I：

10.1111/nure.12055

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Preeclampsia is a pregnancy-specific disorder that affects 2-8% of all pregnancies and remains a leading cause of maternal and perinatal morbidity and mortality worldwide. Diagnosis is based on new onset of hypertension and proteinuria. Multiple organ systems can be affected, with severe disease resulting. The wide range of risk factors reflects the heterogeneity of preeclampsia. Obesity, which is increasing at an alarming rate, is also a risk factor for preeclampsia as well as for later-life cardiovascular disease. Exploring common features may provide insight into the pathophysiologic mechanisms underlying preeclampsia among obese and overweight women. (C) 2013 International Life Sciences Institute

引用

页码：S18 / S25

页数：8

共 85 条

[1] Overview of Maternal Morbidity During Hospitalization for Labor and Delivery in the United States 1993-1997 and 2001-2005 [J].

Berg, Cynthia J. ;

MacKay, Andrea R. ;

Qin, Cheng ;

Callaghan, William M. .

OBSTETRICS AND GYNECOLOGY, 2009, 113 (05) :1075-1081

[2] Pregnancy outcome at age 40 and older [J].

Bianco, A ;

Stone, J ;

Lynch, L ;

Lapinski, R ;

Berkowitz, G ;

Berkowitz, RL .

OBSTETRICS AND GYNECOLOGY, 1996, 87 (06) :917-922

[3] Prepregnancy body mass index and the occurrence of severe hypertensive disorders of pregnancy [J].

Bodnar, Lisa M. ;

Catov, Janet M. ;

Klebanoff, Mark A. ;

Ness, Roberta B. ;

Roberts, James M. .

EPIDEMIOLOGY, 2007, 18 (02) :234-239

[4] Inflammation and triglycerides partially mediate the effect of prepregnancy body mass index on the risk of preeclampsia [J].

Bodnar, LM ;

Ness, RB ;

Harger, GF ;

Roberts, JM .

AMERICAN JOURNAL OF EPIDEMIOLOGY, 2005, 162 (12) :1198-1206

[5] The risk of preeclampsia rises with increasing prepregnancy body mass index [J].

Bodnar, LM ;

Ness, RB ;

Markovic, N ;

Roberts, JM .

ANNALS OF EPIDEMIOLOGY, 2005, 15 (07) :475-482

[6] The Role of Nitric Oxide Synthase Inhibition by Asymmetric Dimethylarginine in the Pathophysiology of Preeclampsia [J].

Boeger, Rainer H. ;

Diemert, Anke ;

Schwedhelm, Edzard ;

Lueneburg, Nicole ;

Maas, Renke ;

Hecher, Kurt .

GYNECOLOGIC AND OBSTETRIC INVESTIGATION, 2010, 69 (01) :1-13

[7] Asymmetric dimethylarginine, derangements of the endothelial nitric oxide synthase pathway, and cardiovascular diseases [J].

Böger, RH ;

Bode-Böger, SM .

SEMINARS IN THROMBOSIS AND HEMOSTASIS, 2000, 26 (05) :539-545

[8] Low-dose aspirin to prevent preeclampsia in women at high risk [J].

Caritis, S ;

Sibai, B ;

Hauth, J ;

Lindheimer, MD ;

Klebanoff, M ;

Thom, E ;

VanDorsten, P ;

Landon, M ;

Paul, R ;

Miodovnik, M ;

Meis, P ;

Thurnau, G .

NEW ENGLAND JOURNAL OF MEDICINE, 1998, 338 (11) :701-705

[9] Risk of early or severe preeclampsia related to pre-existing conditions [J].

Catov, Janet M. ;

Ness, Roberta B. ;

Kip, Kevin E. ;

Olsen, Jorn .

INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2007, 36 (02) :412-419

[10] A longitudinal study of biochemical variables in women at risk of preeclampsia [J].

Chappell, LC ;

Seed, PT ;

Briley, A ;

Kelly, FJ ;

Hunt, BJ ;

Charnock-Jones, DS ;

Mallet, AI ;

Poston, L .

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2002, 187 (01) :127-136

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