Interactions of transition metal ions with N-methylformamide as a peptide bond model system

In this work two new perchlorate based inorganic salts with N-methylformamide (NMF) as a crystal solvate, Cu(ClO4)(2)center dot 4NMF and Ni(ClO4)(2)center dot 6NMF were synthesized and their structures confirmed by X-ray analysis. The influence of water content on absorption spectra M(ClO4)(2)center dot xNMF (where M = Co, Ni or Cu) in water - N-methylformamide mixtures was investigated and overall molar absorption coefficients were calculated. Density, viscosity and electrical conductivity measurements of these salts in NMF were performed at the temperature T = 298.15 K, atmospheric pressure and in the concentration range up to similar to 0.2 mol.dm(-3). All obtained results are compared with those obtained in water. From the calculated volumetric and viscometric parameters, nature of interactions between transition metal ions with peptide bond model system based on NMF were discussed. (C) 2019 Elsevier B.V. All rights reserved.