3D near-infrared imaging based on a single-photon avalanche diode array sensor

被引：0
作者：
Pavia, Juan Mata [1 ,2 ]
Wolf, Martin
Charbon, Edoardo [2 ]
机构：
[1] Univ Spital Zurich, Klin Neonatol, Frauenklin Str 10, CH-8091 Zurich, Switzerland
[2] Quantum Architecture Grp AQUA, EPFL, CH-1015 Lausanne, Switzerland
来源：
BIOSENSING AND NANOMEDICINE V | 2012年 / 8460卷
关键词：
Near-infrared spectroscopy (NIRS); Near-infrared imaging NIRI; Time-resolved imaging; Image reconstruction techniques; Diffuse optical tomography; Inverse problems; CMOS; SPAD; Time-of-flight camera; Single-photon detector; TISSUE; TOMOGRAPHY; DETECTOR;
D O I：
10.1117/12.978029
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Near-infrared light can be used to determine the optical properties (absorption and scattering) of human tissue. Optical tomography uses this principle to image the internal structure of parts of the body by measuring the light that is scattered in the tissue. An imager for optical tomography was designed based on a detector with 128x128 single photon pixels that included a bank of 32 time-to-digital converters. Due to the high spatial resolution and the possibility of performing time resolved measurements, a new contactless setup has been conceived. The setup has a resolution of 97ps and operates with a laser source with an average power of 3mW. This new setup generated an high amount of data that could not be processed by established methods, therefore new concepts and algorithms were developed to take advantage of it. Simulations show that the potential resolution of the new setup would be much higher than previous designs. Measurements have been performed showing its potential. Images derived from the measurements showed that it is possible to reach a resolution of at least 5mm.
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页数：6
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