Polyanalgesic Consensus Conference-2012: Recommendations on Trialing for Intrathecal (Intraspinal) Drug Delivery: Report of an Interdisciplinary Expert Panel

被引：52

作者：

Deer, Timothy R. ^{[1
]}

Prager, Joshua ^{[2
]}

Levy, Robert ^{[3
]}

Burton, Allen ^{[4
]}

Buchser, Eric ^{[5
]}

Caraway, David ^{[6
]}

Cousins, Michael ^{[7
]}

De Andres, Jose ^{[8
,36
]}

Diwan, Sudhir ^{[9
]}

Erdek, Michael ^{[10
,34
,35
]}

Grigsby, Eric ^{[11
,33
]}

Huntoon, Marc ^{[12
]}

Jacobs, Marilyn ^{[2
]}

Kim, Phillip ^{[13
,32
]}

Kumar, Krishna ^{[14
]}

Leong, Michael ^{[15
]}

Liem, Liong ^{[16
]}

McDowell, Gladstone ^{[17
]}

Panchal, Sunil J. ^{[18
]}

Rauck, Richard ^{[19
,37
]}

Saulino, Michael ^{[20
,31
]}

Staats, Peter ^{[21
]}

Stanton-Hicks, Michael ^{[22
]}

Stearns, Lisa ^{[23
]}

Sitzman, B. Todd ^{[24
]}

Wallace, Mark

Willis, K. Dean ^{[25
,30
]}

Witt, William ^{[26
,29
]}

Yaksh, Tony ^{[27
]}

Mekhail, Nagy ^{[28
]}

机构：

[1] Ctr Pain Relief, Charleston, WV 25301 USA

[2] Univ Calif Los Angeles, Los Angeles, CA USA

[3] Univ Florida, Jacksonville, FL USA

[4] Houston Pain Associates LLC, Houston, TX USA

[5] EHC Hosp, Anesthesia & Pain Management Dept, Morges, Switzerland

[6] Tri City, Ctr Pain Relief, Huntington, WV USA

[7] Kolling Inst Med Res, Sydney, NSW, Australia

[8] Univ Valencia, Sch Med, Valencia, Spain

[9] Spine & Pain Inst New York, Staten Isl, NY USA

[10] Johns Hopkins Univ, Sch Med, Dept Anesthesiol, Baltimore, MD USA

[11] Queen Valley Hosp, Napa Pain Inst, Napa Surg Ctr, Napa, CA USA

[12] Vanderbilt Univ, Nashville, TN USA

[13] Christiana Hosp, Newark, DE USA

[14] Univ Saskatchewan, Saskatoon, SK, Canada

[15] Stanford Univ, Palo Alto, CA 94304 USA

[16] St Antonius Hosp, Nieuwegein, Netherlands

[17] Integrated Pain Solut, Columbus, OH USA

[18] Natl Inst Pain, Tampa, FL USA

[19] Wake Forest Univ Baptist Hlth, Winston Salem, NC USA

[20] Thomas Jefferson Univ, Jefferson Med Coll, Dept Rehabil Med, Philadelphia, PA 19107 USA

[21] Metzger Staats Pain Management, Shrewsbury, NJ USA

[22] Cleveland Clin, Anesthesia Inst, Dept Pain Management & Res, Cleveland, OH 44106 USA

[23] Arizona Canc Pain & Surg Ctr, Phoenix, AZ USA

[24] Adv Pain Therapy PLLC, Hattiesburg, MS USA

[25] Alabama Pain Ctr, Huntsville, AL USA

[26] Cardinal Hill Rehabil Hosp, Lexington, KY USA

[27] Univ Calif San Diego, Dept Anesthesiol, San Diego, CA 92103 USA

[28] Cleveland Clin, Dept Pain Management, Cleveland, OH 44106 USA

[29] Univ Kentucky, Lexington, KY USA

[30] Univ Alabama Birmingham, Sch Nursing, Birmingham, AL USA

[31] Thomas Jefferson Univ, Jefferson Med Coll, MossRehab, Philadelphia, PA 19107 USA

[32] Bryn Mawr Hosp, Bryn Mawr, PA USA

[33] St Helena Hosp, Napa, CA USA

[34] Johns Hopkins Univ, Sch Med, Dept Crit Care Med, Baltimore, MD USA

[35] Johns Hopkins Univ, Sch Med, Dept Oncol, Baltimore, MD 21205 USA

[36] Gen Univ Hosp, Valencia, Spain

[37] Carolinas Pain Inst, Winston Salem, NC USA

来源：

NEUROMODULATION | 2012年 / 15卷 / 05期

关键词：

Chronic pain; consensus; intrathecal; trialing; REFRACTORY CANCER PAIN; OPIOID THERAPY; MORPHINE INFUSION; SPINAL SPASTICITY; NEUROPATHIC PAIN; NONCANCER PAIN; ZICONOTIDE; BACLOFEN; PATIENT; BACK;

D O I：

10.1111/j.1525-1403.2012.00450.x

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Introduction: Trialing for intrathecal pump placement is an essential part of the decision-making process in placing a permanent device. In both the United States and the international community, the proper method for trialing is ill defined. Methods: The Polyanalgesic Consensus Conference (PACC) is a group of well-published experienced practitioners who meet to update the state of care for intrathecal therapies on the basis of current knowledge in the literature and clinical experience. Anexhaustive search is performed to create a base of information that the panel considers when making recommendations for best clinical practices. This literature, coupled with clinical experience, is the basis for recommendations and for identification of gaps in the base of knowledge regarding trialing for intrathecal pump placement. Results: The panel has made recommendations for the proper methods of trialing for long-term intrathecal drug delivery. Conclusion: The use of intrathecal drug delivery is an important part of the treatment algorithm for moderate to severe chronic pain. It has become common practice to perform a temporary neuroaxial infusion before permanent device implantation. On the basis of current knowledge, the PACC has developed recommendations to improve care. The need to update these recommendations will be very important as new literature is published.

引用

页码：420 / 435

页数：16

共 44 条

[41] Pharmacokinetics and pharmacodynamics of intrathecal ziconotide in chronic pain patients [J].