Lab-on-a-chip for high frequency acoustic characterization

被引:6
|
作者
Gao, Jiaming [1 ,2 ]
Carlier, Julien [1 ]
Wang, Shengxiang [3 ]
Campistron, Pierre [1 ]
Callens, Dorothee [1 ]
Guo, Shishang [2 ]
Zhao, Xingzhong [2 ]
Nongaillard, Bertrand [1 ]
机构
[1] Univ Lille Nord France, UVHC, IEMN, DOAE,CNRS,UMR 8520, F-59313 Valenciennes, France
[2] Wuhan Univ, Dept Phys, Wuhan 430072, Peoples R China
[3] Wuhan Text Univ, Sch Elect & Elect Engn, Wuhan 430073, Peoples R China
来源
SENSORS AND ACTUATORS B-CHEMICAL | 2013年 / 177卷
关键词
Ultra high frequency transducer; Acoustical characterization; Lab-on-a-chip; Microfluidics; Bulk acoustic wave; SYSTEMS; NANOCOMPOSITES; MICROFLUIDICS; MANIPULATION;
D O I
10.1016/j.snb.2012.11.037
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
This paper presents an acoustofluidics platform for elastic characterization of biological samples using ultra high frequency (similar to 1 GHz) ultrasonic bulk acoustic waves (BAW). The propagation of bulk acoustic waves in a plane parallel to the surface of a silicon wafer was controlled using 45 degrees acoustic mirrors, thus leading to the development of real time biosensing applications in a microchannel fabricated using ICP technology. To validate the design and technology of the silicon and PDMS-based platform, the propagation of bulk acoustic waves through the microfluidic channel was studied. This lab-on-a-chip platform was used to characterize different concentrations of chemical solutions in the microfluidic channel and detect latex particles passing through the channel. (c) 2012 Elsevier B.V. All rights reserved.
引用
收藏
页码:753 / 760
页数:8
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