Sodium tetrafluoroborate as a new and highly efficient catalyst for one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones and thiones

被引：15

作者：

Bandgar, B. P. ^{[1
]}

Kamble, V. T. ^{[1
]}

Bavikar, S. N. ^{[1
]}

Dhavane, Abasalleb ^{[1
]}

机构：

[1] Swami Ramananad Teerth Marathwada Univ, Sch Chem Sci, Organ Chem Res Lab, Nanded 431606, India

来源：

JOURNAL OF THE CHINESE CHEMICAL SOCIETY | 2007年 / 54卷 / 02期

关键词：

sodium tetrafluoroborate; aldehyde; 1,3-dicarbonyl compound; urea; thiourea;

D O I：

10.1002/jccs.200700038

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Sodium tetrafluoroborate (NaBF4) is found to catalyze the three component condensation of an aldehyde, 1,3-dicarbonyl compound and urea or thiourea to afford the corresponding 3,4-dihydropyrimidin-2(1H)-ones and thiones in high yields. This method is very useful for the synthesis of a wide range of 3,4-dihydropyrimidin-2(1H)-ones and thiones from aromatic, heterocyclic, alpha, beta-unsaturated aldehydes and aliphatic aldehydes.

引用

页码：263 / 266

页数：4

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