Should we routinely use modified Atkins diet instead of regular ketogenic diet to treat children with epilepsy?

被引：30

作者：

Auvin, Stephane ^{[1
,2
,3
]}

机构：

[1] Hop Robert Debre, APHP, Serv Neurol Pediat, F-75019 Paris, France

[2] INSERM, U676, Paris, France

[3] Univ Paris Diderot, INSERM, UMR676, Paris, France

来源：

SEIZURE-EUROPEAN JOURNAL OF EPILEPSY | 2012年 / 21卷 / 04期

关键词：

Epilepsy; Ketogenic diet; Atkins diet; INTRACTABLE CHILDHOOD EPILEPSY; GLUT1; DEFICIENCY; CALORIE RESTRICTION; STATUS EPILEPTICUS; INFANTILE SPASMS; EFFICACY; ADULTS; ONSET; EXPERIENCE; TRIAL;

D O I：

10.1016/j.seizure.2012.02.005

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The modified Atkins diet (MAD) consists of a nearly balanced diet without any age-dependent restriction of recommended daily calorie intake. Recently, there has been a marked increase in the use of the MAD in the treatment of epilepsy. Over the last 8 years, evidence suggesting that the MAD may exhibit similar anticonvulsant properties as the traditional ketogenic diet (KD) has been accumulating. KD is now an 'evidence-based' treatment for refractory epilepsy. Although there are currently no direct comparisons data from the literature suggest that the MD is more efficacious than the MAD. However, the MAD is easier to administer and has better tolerability. This review discusses when to consider each diet. The MAD may be the first diet of choice. In case of insufficient efficacy under the MAD, a switch from the MAD to the MD should be considered. (C) 2012 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.

引用

页码：237 / 240

页数：4

共 38 条

[1] Mild adolescent/adult onset epilepsy and paroxysmal exercise-induced dyskinesia due to GLUT1 deficiency [J].

Afawi, Zaid ;

Suls, Arvid ;

Ekstein, Dana ;

Kivity, Sara ;

Neufeld, Miriam Y. ;

Oliver, Karen ;

De Jonghe, Peter ;

Korczyn, Amos D. ;

Berkovic, Samuel F. .

EPILEPSIA, 2010, 51 (12) :2466-2469

[2] Effectiveness of the ketogenic diet in a broad range of seizure types and EEG features for severe childhood epilepsies [J].

Beniczky, S. ;

Miranda, M. Jose ;

Alving, J. ;

Povlsen, J. Heber ;

Wolf, P. .

ACTA NEUROLOGICA SCANDINAVICA, 2010, 121 (01) :58-62

[3] Interest of the ketogenic:: diet in a refractory status epilepticus in adults [J].

Bodenant, M. ;

Moreau, C. ;

Sejourne, C. ;

Auvin, S. ;

Delval, A. ;

Cuisset, J. -M. ;

Derambure, P. ;

Destee, A. ;

Defebvre, L. .

REVUE NEUROLOGIQUE, 2008, 164 (02) :194-199

[4] Calorie restriction and ketogenic diet diminish neuronal excitability in rat dentate gyrus in vivo [J].

Bough, KJ ;

Schwartzkroin, PA ;

Rho, JM .

EPILEPSIA, 2003, 44 (06) :752-760

[5] Seizure resistance is dependent upon age and calorie restriction in rats fed a ketogenic diet [J].

Bough, KJ ;

Valiyil, R ;

Han, FT ;

Eagles, DA .

EPILEPSY RESEARCH, 1999, 35 (01) :21-28

[6]

Caraballo RH, 2006, EPILEPTIC DISORD, V8, P151

[7] A pilot trial with modified Atkins' diet in adult patients with refractory epilepsy [J].

Carrette, Evelien ;

Vonck, Kristl ;

de Herdt, Veerle ;

Dewaele, Isabelle ;

Raedt, Robrecht ;

Goossens, Lut ;

Van Zandijcke, Michel ;

Wadman, Wytse ;

Thadani, Vijay ;

Boon, Paul .

CLINICAL NEUROLOGY AND NEUROSURGERY, 2008, 110 (08) :797-803

[8] The Ketogenic Diet for Medically and Surgically Refractory Status Epilepticus in the Neurocritical Care Unit [J].

Cervenka, Mackenzie C. ;

Hartman, Adam L. ;

Venkatesan, Arun ;

Geocadin, Romergryko G. ;

Kossoff, Eric H. .

NEUROCRITICAL CARE, 2011, 15 (03) :519-524

[9] Ketogenic diet for treatment of infantile spasms [J].

Eun, So Hee ;

Kang, Hoon Chul ;

Kim, Dong Wook ;

Kim, Heung Dong .

BRAIN & DEVELOPMENT, 2006, 28 (09) :566-571

[10] The efficacy of the ketogenic diet - 1998: A prospective evaluation of intervention in 150 children [J].

Freeman, JM ;

Vining, EPG ;

Pillas, DJ ;

Pyzik, PL ;

Casey, JC ;

Kelly, MT .

PEDIATRICS, 1998, 102 (06) :1358-1363

← 1 2 3 4 →