Model Studies on the Synthesis of Madangamine Alkaloids. Assembly of the Macrocyclic Rings

被引：20
作者：
Proto, Stefano
Amat, Mercedes [1 ]
Perez, Maria
Ballette, Roberto
Romagnoli, Federica
Mancinelli, Andrea
Bosch, Joan
机构：
[1] Univ Barcelona, Fac Pharm, Organ Chem Lab, E-08028 Barcelona, Spain
来源：
ORGANIC LETTERS | 2012年 / 14卷 / 15期
关键词：
DIAZATRICYCLIC CORE; MARINE ALKALOIDS; TRICYCLIC CORE;
D O I：
10.1021/ol301672y
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Using simplified model derivatives, the assembly of the macrocyclic rings of madangamines, including the 13- and 14-membered D rings of madangamlnes C-E, the all-cis-triunsaturated 15-membered D ring of madangamine A, and the (Z,Z)-unsaturated 11-membered E ring common to madangamines A-E, has been studied.
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收藏
页码：3916 / 3919
页数：4
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