Electrocardiographic features in a patient with the coexistence of long QT syndrome and coronary vasospasm

被引：7

作者：

Tanaka, Yasuaki ^{[1
]}

Nishizaki, Mitsuhlro ^{[1
]}

Yamawake, Noriyoshi ^{[1
]}

Sakurada, Harumtzu ^{[2
]}

Hiraoka, Masayasu ^{[3
]}

机构：

[1] Yokohama Minami Kyosai Hosp, Dept Cardiol, Kanazawa Ku, Kanagawa, Japan

[2] Tokyo Metropolitan Hiroo Gen Hosp, Dept Cardiol, Tokyo, Japan

[3] Tokyo Med & Dent Univ, Tokyo, Japan

来源：

PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY | 2008年 / 31卷 / 08期

关键词：

long QT; vasospastic angina; coronary vasospasm; VF; sudden cardiac death; ion channel; acetylcholine; epinephrine; glucose; insulin; ICD;

D O I：

10.1111/j.1540-8159.2008.01137.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 20-year-old woman suffered from cardiopulmonary arrest due to ventricular fibrillation. The electrocardiogram after resuscitation showed prolonged QTc interval with bifid T wave. On the third hospital day, the QTc interval and the T-wave changes improved. However, the QTc interval was distinctively prolonged after administration of epinephrine, oral glucose load, and intracoronary acetylcholine (Ach) into the left coronary artery. Moreover, an injection of Ach into the right coronary artery provoked severe coronary spasm. This is a case of the coexistence of long QT syndrome (LQTS) and coronary vasospasm, which may give an important clinical implication for the treatment of LQTS.

引用

页码：1065 / 1069

页数：5

共 20 条

[1] Acetylcholine-induced prolongation of the QT interval in idiopathic long QT syndrome
Aizawa, Y
Washizuka, T
Igarashi, Y
Kitazawa, H
Chinushi, M
Abe, A
Shibata, A
[J]. AMERICAN JOURNAL OF CARDIOLOGY, 1996, 77 (10) : 879 - &
[2] Insulin stimulates the L-type Ca2+ current in rat cardiac myocytes
Aulbach, F
Simm, A
Maier, S
Langenfeld, H
Walter, U
Kersting, U
Kirstein, M
[J]. CARDIOVASCULAR RESEARCH, 1999, 42 (01) : 113 - 120
[3] A MOLECULAR-BASIS FOR CARDIAC-ARRHYTHMIA - HERG MUTATIONS CAUSE LONG QT SYNDROME
CURRAN, ME
SPLAWSKI, I
TIMOTHY, KW
VINCENT, GM
GREEN, ED
KEATING, MT
[J]. CELL, 1995, 80 (05) : 795 - 803
[4] Effect of atropine on QT prolongation and torsade de pointes induced by intracoronary acetylcholine in the long QT syndrome
Furushima, H
Niwano, S
Chinushi, M
Yamaura, M
Taneda, K
Washizuka, T
Aizawa, Y
[J]. AMERICAN JOURNAL OF CARDIOLOGY, 1999, 83 (05) : 714 - 718
[5] HUCKELL VF, 1981, BRIT HEART J, V45, P649
[6] THE LONG QT SYNDROME - A PROSPECTIVE INTERNATIONAL STUDY
MOSS, AJ
SCHWARTZ, PJ
CRAMPTON, RS
LOCATI, E
CARLEEN, E
[J]. CIRCULATION, 1985, 71 (01) : 17 - 21
[7] Effectiveness and limitations of β-blocker therapy in congenital long-QT syndrome
Moss, AJ
Zareba, W
Hall, WJ
Schwartz, PJ
Crampton, RS
Benhorin, J
Vincent, GM
Locati, EH
Priori, SG
Napolitano, C
Medina, A
Zhang, L
Robinson, JL
Timothy, K
Towbin, JA
Andrews, ML
[J]. CIRCULATION, 2000, 101 (06) : 616 - 623
[8] ECG T-WAVE PATTERNS IN GENETICALLY DISTINCT FORMS OF THE HEREDITARY LONG QT SYNDROME
MOSS, AJ
ZAREBA, W
BENHORIN, J
LOCATI, EH
HALL, WJ
ROBINSON, JL
SCHWARTZ, PJ
TOWBIN, JA
VINCENT, GM
LEHMANN, MH
KEATING, MT
MACCLUER, JW
TIMOTHY, KW
[J]. CIRCULATION, 1995, 92 (10) : 2929 - 2934
[9] Effects of glucose-induced insulin secretion on ventricular repolarization in patients with congenital long QT syndrome
Nishizaki, M
Ashikaga, T
Yamawake, N
Fujii, H
Arita, M
Sumitomo, N
Sakurada, H
Hiraoka, M
[J]. CIRCULATION JOURNAL, 2002, 66 (01) : 35 - 40
[10] Gene-specific response of dynamic ventricular repolarization to sympathetic stimulation in LQT1, LQT2 and LQT3 forms of congenital long QT syndrome
Noda, T
Takaki, H
Kurita, T
Suyama, K
Nagaya, N
Taguchi, A
Aihara, N
Kamakura, S
Sunagawa, K
Nakamura, K
Ohe, T
Horie, M
Napolitano, C
Towbin, JA
Priori, SG
Shimizu, W
[J]. EUROPEAN HEART JOURNAL, 2002, 23 (12) : 975 - 983

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