ANTISTAPHYBASE: database of antimicrobial peptides (AMPs) and essential oils (EOs) against methicillin-resistant Staphylococcus aureus (MRSA) and Staphylococcus aureus

被引：17

作者：

Zouhir, Abdelmajid ^{[1
,2
]}

Taieb, Malek ^{[3
]}

Lamine, Mohamed Ashraf ^{[1
,2
]}

Cherif, Ammar ^{[4
]}

Jridi, Taoufik ^{[1
,2
]}

Mahjoubi, Basma ^{[1
,2
]}

Mbarek, Sarra ^{[1
,2
]}

Fliss, Ismail ^{[5
]}

Nefzi, Adel ^{[6
]}

Sebei, Khaled ^{[1
,2
]}

Ben Hamida, Jeannette ^{[1
,2
]}

机构：

[1] Univ Tunis ELMANAR, Nutraceut & Funct Prote Potential Biodivers Tunis, Tunis, Tunisia

[2] Inst Appl Biol Sci Tunis ISSBAT, Res Unit, Tunis, Tunisia

[3] Univ Gabes, Fac Sci Gabes, Gabes, Tunisia

[4] Univ El Manar, Fac Sci Tunis, Tunis, Tunisia

[5] Univ Laval, INAF, Quebec City, PQ, Canada

[6] Torrey Pines Inst Mol Studies, Port St Lucie, FL USA

来源：

ARCHIVES OF MICROBIOLOGY | 2017年 / 199卷 / 02期

关键词：

Anti-MRSA peptides; Anti-MRSA EOs; Anti-S. aureus peptides; Anti-S. aureus EOs; EPIDEMIOLOGY;

D O I：

10.1007/s00203-016-1293-6

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Staphylococcus aureus and methicillin-resistant S. aureus are major pathogens. The antimicrobial peptides and essential oils (EOs) display narrow- or broad-spectrum activity against bacteria including these strains. A centralized resource, such as a database, designed specifically for anti-S. aureus/anti-methicillin-resistant S. aureus antimicrobial peptides and EOs is therefore needed to facilitate the comprehensive investigation of their structure/activity associations and combinations. The database ANTISTAPHYBASE is created to facilitate access to important information on antimicrobial peptides and essential peptides against methicillin-resistant S. aureus and S. aureus. At the moment, the database contains 596 sequences of antimicrobial peptides produced by diverse organisms and 287 essential oil records. It permits a quick and easy search of peptides based on their activity as well as their general, physicochemical properties and literature data. These data are very useful to perform further bioinformatic or chemometric analysis and would certainly be useful for the development of new drugs for medical use. The ANTISTAPHYBASE database is freely available at: https://www.antistaphybase.com/.

引用

页码：215 / 222

页数：8

共 37 条

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