Drug delivery systems for resveratrol, a non-flavonoid polyphenol: Emerging evidence in last decades

被引：97

作者：

Ahmadi, Zahra ^{[1
]}

Mohammadinejad, Reza ^{[2
]}

Ashrafizadeh, Milad ^{[1
]}

机构：

[1] Kerman Univ Med Sci, Neurosci Res Ctr, Inst Neuropharmacol, Kerman, Iran

[2] Kerman Univ Med Sci, Pharmaceut Res Ctr, Inst Neuropharmacol, Kerman, Iran

来源：

JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY | 2019年 / 51卷

关键词：

Resveratrol; Bioavailability; Cancer therapy; Drug delivery; Nanostructures; SOLID LIPID NANOPARTICLES; MESOPOROUS SILICA NANOPARTICLES; CO-ENCAPSULATED RESVERATROL; IN-VITRO; GOLD NANOPARTICLES; ANTIOXIDANT ACTIVITY; PLGA NANOPARTICLES; POLYMERIC MICELLES; ULTRADEFORMABLE LIPOSOMES; COMBINATION THERAPY;

D O I：

10.1016/j.jddst.2019.03.017

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Resveratrol is a naturally occurring non-flavonoid polyphenol which is found in a variety of plants, where it responses to the injury or fungal attack. This important compound has different beneficial activities such as antioxidant, antitumor, anti-inflammatory and antiaging. Also, it has anti-fibrotic and hepatoprotective effects. Besides the beneficial effects of resveratrol, limitations such as poor solubility in water, low oxidative stability and high photosensitivity have restricted its application. To prevail to these restrictions, nanotechnology is a smart strategy. This review discusses various kinds of nano delivery systems that have been applied for enclosing resveratrol.

引用

页码：591 / 604

页数：14

共 139 条

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