Natural neo acids and neo alkanes: Their analogs and derivatives

被引：27
作者：
Dembitsky, Valery M. [1 ]
机构：
[1] Hebrew Univ Jerusalem, Dept Med Chem & Nat Prod, Sch Pharm, IL-91120 Jerusalem, Israel
来源：
LIPIDS | 2006年 / 41卷 / 04期
关键词：
D O I：
10.1007/s11745-006-5103-9
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
This review presents more than 260 naturally occurring (as well as 47 synthesized) neo fatty (carboxylic) acids, neo alkanes, and their analogs and derivatives, isolated and identified from plants, algae, fungi, marine invertebrates, and microorganisms, that demonstrate different biological activities. These natural metabolites are good prospects for future chemical preparations as antioxidants, and also as anticancer, antimicrobial, and antibacterial agents. Described also are some synthetic bioactive compounds containing a tertiary butyl group(s) that have shown high anticancer, antifungal, and other activities. Applications of some neo fatty (carboxylic) acid derivatives in cosmetic, agronomic, and pharmaceutical industries also are considered. This is the first review to consider naturally occurring neo fatty (carboxylic) acids, neo alkanes, and other metabolites containing a tertiary butyl group(S)
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页码：309 / 340
页数：32
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