Maternal determinants of embryonic cell fate

被引：52

作者：

Heasman, J ^{[1
]}

机构：

[1] Childrens Hosp Res Fdn, Div Dev Biol ML7007, Cincinnati, OH 45229 USA

来源：

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY | 2006年 / 17卷 / 01期

关键词：

maternal; localization; Wnt11; VegT; ectodermin; antisense;

D O I：

10.1016/j.semcdb.2005.11.005

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

How important is the contribution of mRNAs and proteins stored in the oocyte for determining the body plan of the Xenopus embryo? Here we review the current understanding of the roles of maternally Supplied transcription factors, signaling molecules, and signaling regulators in establishing the ectoderm, mesoderm, and endoderm germ layers and the embryonic axes. Key essential asymmetries of VegT, Wntl 1, and Ectodermin are described, as well as the complexity of maternal transcription factors that are involved in the initial expression of early zygotic genes. (C) 2005 Elsevier Ltd. All rights reserved.

引用

页码：93 / 98

页数：6

共 76 条

[1] Cell fate specification and competence by Coco, a maternal BMP, TGFβ and Wnt inhibitor [J].

Bell, E ;

Muñoz-Sanjuán, I ;

Altmann, CR ;

Vonica, A ;

Brivanlou, AH .

DEVELOPMENT, 2003, 130 (07) :1381-1389

[2] XPACE4 is a localized pro-protein convertase required for mesoderm induction and the cleavage of specific TGFβ proteins in Xenopus development [J].

Birsoy, B ;

Berg, L ;

Williams, PH ;

Smith, JC ;

Wylie, CC ;

Christian, JL ;

Heasman, J .

DEVELOPMENT, 2005, 132 (03) :591-602

[3] Twisted gastrulation loss-of-function analyses support its role as a BMP inhibitor during early Xenopus ernbryogenesis [J].

Blitz, IL ;

Cho, KWY ;

Chang, CB .

DEVELOPMENT, 2003, 130 (20) :4975-4988

[4] Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer [J].

Bouwmeester, T ;

Kim, SH ;

Sasai, Y ;

Lu, B ;

DeRobertis, EM .

NATURE, 1996, 382 (6592) :595-601

[5] Roles of NPM2 in chromatin and nucleolar organization in oocytes and embryos [J].

Burns, KH ;

Viveiros, MM ;

Ren, YS ;

Wang, P ;

DeMayo, FJ ;

Frail, DE ;

Eppig, JJ ;

Matzuk, MM .

SCIENCE, 2003, 300 (5619) :633-636

[6] A transcriptional partner for MAD proteins in TGF-beta signalling [J].

Chen, X ;

Rubock, MJ ;

Whitman, M .

NATURE, 1996, 383 (6602) :691-696

[7] MOLECULAR NATURE OF SPEMANNS ORGANIZER - THE ROLE OF THE XENOPUS HOMEOBOX GENE GOOSECOID [J].

CHO, KWY ;

BLUMBERG, B ;

STEINBEISSER, H ;

DEROBERTIS, EM .

CELL, 1991, 67 (06) :1111-1120

[8] BONE MORPHOGENETIC PROTEIN-2 IN THE EARLY DEVELOPMENT OF XENOPUS-LAEVIS [J].

CLEMENT, JH ;

FETTES, P ;

KNOCHEL, S ;

LEF, J ;

KNOCHEL, W .

MECHANISMS OF DEVELOPMENT, 1995, 52 (2-3) :357-370

[9] XOTCH, THE XENOPUS HOMOLOG OF DROSOPHILA-NOTCH [J].

COFFMAN, C ;

HARRIS, W ;

KINTNER, C .

SCIENCE, 1990, 249 (4975) :1438-1441

[10] Links between tumor suppressors:: p53 is required for TGF-β gene responses by cooperating with Smads [J].

Cordenonsi, M ;

Dupont, S ;

Maretto, S ;

Insinga, A ;

Imbriano, C ;

Piccolo, S .

CELL, 2003, 113 (03) :301-314

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