Tau Prion-Like Propagation: State of the Art and Current Challenges

被引:48
作者
Dujardin, Simon [1 ]
Hyman, Bradley T. [1 ]
机构
[1] Harvard Med Sch, MassGen Inst Neurodegenerat Dis, Massachusetts Gen Hosp, Dept Neurol, Charlestown, MA 02129 USA
来源
TAU BIOLOGY | 2019年 / 1184卷
关键词
PROGRESSIVE SUPRANUCLEAR PALSY; PAIRED HELICAL FILAMENTS; ALPHA-SYNUCLEIN FIBRILS; TO-NEURON TRANSMISSION; ALZHEIMERS-DISEASE; PATHOLOGICAL TAU; AMYLOID-BETA; NEUROFIBRILLARY TANGLES; REGIONAL VULNERABILITY; SYNAPTIC DYSFUNCTION;
D O I
10.1007/978-981-32-9358-8_23
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:305 / 325
页数:21
相关论文
共 162 条
[1]   Tunneling nanotubes: A possible highway in the spreading of tau and other prion-like proteins in neurodegenerative diseases [J].
Abounit, Saida ;
Wu, Jessica W. ;
Duff, Karen ;
Victoria, Guiliana Soraya ;
Zurzolo, Chiara .
PRION, 2016, 10 (05) :344-351
[2]   Three Repeat Isoforms of Tau Inhibit Assembly of Four Repeat Tau Filaments [J].
Adams, Stephanie J. ;
DeTure, Michael A. ;
McBride, Melinda ;
Dickson, Dennis W. ;
Petrucelli, Leonard .
PLOS ONE, 2010, 5 (05)
[3]   The Transcellular Spread of Cytosolic Amyloids, Prions, and Prionoids [J].
Aguzzi, Adriano ;
Rajendran, Lawrence .
NEURON, 2009, 64 (06) :783-790
[4]   A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity [J].
Ahmed, Zeshan ;
Cooper, Jane ;
Murray, Tracey K. ;
Garn, Katya ;
McNaughton, Emily ;
Clarke, Hannah ;
Parhizkar, Samira ;
Ward, Mark A. ;
Cavallini, Annalisa ;
Jackson, Samuel ;
Bose, Suchira ;
Clavaguera, Florence ;
Tolnay, Markus ;
Lavenir, Isabelle ;
Goedert, Michel ;
Hutton, Michael L. ;
O'Neill, Michael J. .
ACTA NEUROPATHOLOGICA, 2014, 127 (05) :667-683
[5]   Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes [J].
Alvarez-Erviti, Lydia ;
Seow, Yiqi ;
Yin, HaiFang ;
Betts, Corinne ;
Lakhal, Samira ;
Wood, Matthew J. A. .
NATURE BIOTECHNOLOGY, 2011, 29 (04) :341-U179
[6]   Fibrillogenic nuclei composed of P301L mutant tau induce elongation of P301L Tau but not wild-type Tau [J].
Aoyagi, Hirofumi ;
Hasegawa, Masato ;
Tamaoka, Akira .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (28) :20309-20318
[7]   The Topographical and Neuroanatomical Distribution of Neurofibrillary Tangles and Neuritic Plaques in the Cerebral Cortex of Patients with Alzheimer's Disease [J].
Arnold, Steven E. ;
Hyman, Bradley T. ;
Flory, Jill ;
Damasio, Antonio R. ;
Van Hoesen, Gary W. .
CEREBRAL CORTEX, 1991, 1 (01) :103-116
[8]   Depletion of microglia and inhibition of exosome synthesis halt tau propagation [J].
Asai, Hirohide ;
Ikezu, Seiko ;
Tsunoda, Satoshi ;
Medalla, Maria ;
Luebke, Jennifer ;
Haydar, Tank ;
Wolozin, Benjamin ;
Butovsky, Oleg ;
Kuegler, Sebastian ;
Ikezu, Tsuneya .
NATURE NEUROSCIENCE, 2015, 18 (11) :1584-1593
[9]   Enhanced Tau Aggregation in the Presence of Amyloid β [J].
Bennett, Rachel E. ;
DeVos, Sarah L. ;
Dujardin, Simon ;
Corjuc, Bianca ;
Gor, Rucha ;
Gonzalez, Jose ;
Roe, Allyson D. ;
Frosch, Matthew P. ;
Pitstick, Rose ;
Carlson, George A. ;
Hyman, Bradley T. .
AMERICAN JOURNAL OF PATHOLOGY, 2017, 187 (07) :1601-1612
[10]   A Review of Fluid Biomarkers for Alzheimer’s Disease: Moving from CSF to Blood [J].
Blennow K. .
Neurology and Therapy, 2017, 6 (Suppl 1) :15-24