Heavy metal-associated isoprenylated plant protein (HIPP): characterization of a family of proteins exclusive to plants

被引：206

作者：

de Abreu-Neto, Joao Braga ^{[1
]}

Turchetto-Zolet, Andreia C. ^{[2
]}

Valter de Oliveira, Luiz Felipe ^{[2
]}

Bodanese Zanettini, Maria Helena ^{[2
]}

Margis-Pinheiro, Marcia ^{[1
,2
]}

机构：

[1] Univ Fed Rio Grande do Sul, Programa Posgrad Biol Celular & Mol, BR-90046900 Porto Alegre, RS, Brazil

[2] Univ Fed Rio Grande do Sul, Programa Posgrad Genet & Biol Mol, BR-90046900 Porto Alegre, RS, Brazil

来源：

FEBS JOURNAL | 2013年 / 280卷 / 07期

关键词：

abiotic stress; heavy metal homeostasis; HIPP; isoprenylated proteins; metallochaperone; COPPER TRAFFICKING; GENE-EXPRESSION; CHAPERONE; RESISTANCE; TOLERANCE; PROLINE; PREDICTION; RESPONSES; ALIGNMENT; EXPOSURE;

D O I：

10.1111/febs.12159

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Metallochaperones are key proteins for the safe transport of metallic ions inside the cell. HIPPs (heavy metal-associated isoprenylated plant proteins) are metallochaperones that contain a metal binding domain (HMA) and a Cterminal isoprenylation motif. In this study, we provide evidence that proteins of this family are found only in vascular plants and may be separated into five distinct clusters. HIPPs may be involved in (a) heavy metal homeostasis and detoxification mechanisms, especially those involved in cadmium tolerance, (b) transcriptional responses to cold and drought, and (c) plantpathogen interactions. In particular, our results show that the rice (Oryzasativa) HIPP OsHIPP41 gene is highly expressed in response to cold and drought stresses, and its product is localized in the cytosol and the nucleus. The results suggest that HIPPs play an important role in the development of vascular plants and in plant responses to environmental changes.

引用

页码：1604 / 1616

页数：13

共 54 条

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