Treatments in context: transcranial direct current brain stimulation as a potential treatment in pediatric psychosis

被引：0

作者：

David, Christopher N. ^{[1
]}

Rapoport, Judith L. ^{[1
]}

Gogtay, Nitin ^{[1
]}

机构：

[1] NIMH, Child Psychiat Branch, NIH, Bethesda, MD 20890 USA

来源：

EXPERT REVIEW OF NEUROTHERAPEUTICS | 2013年 / 13卷 / 04期

关键词：

childhood-onset schizophrenia; pediatric psychosis treatment; transcranial direct current stimulation; CHILDHOOD-ONSET SCHIZOPHRENIA; HUMAN MOTOR CORTEX; DORSOLATERAL PREFRONTAL CORTEX; CORTICAL SPREADING DEPRESSION; RANDOM NOISE STIMULATION; DOUBLE-BLIND; ELECTRICAL-STIMULATION; MAGNETIC STIMULATION; ANODAL POLARIZATION; PARKINSONS-DISEASE;

D O I：

10.1586/ERN.13.29

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Childhood-onset schizophrenia is a chronic, severe form of schizophrenia, and is typically treatment resistant. Even after optimized pharmacotherapy, a majority (over 70%) of these pediatric patients present lasting psychotic symptoms and impaired cognition, necessitating the need for novel treatment modalities. Recent work in transcranial magnetic stimulation suggests moderate efficacy in symptom reduction in adult patients with schizophrenia; however, the transcranial magnetic stimulation treatment is cumbersome for this severely ill population. Transcranial direct current stimulation may provide a safe and effective adjuvant treatment for continued residual symptoms of schizophrenia.

引用

页码：447 / 458

页数：12

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