Facile synthesis of a pentasaccharide repeating unit corresponding to the common O-antigen of Salmonella enterica O57 and Escherichia coli O51

被引：7
作者：
Ghosh, Tamashree [1 ]
Santra, Abhishek [1 ]
Misra, Anup Kumar [1 ]
机构：
[1] Bose Inst, Div Mol Med, Kolkata 700054, India
来源：
TETRAHEDRON-ASYMMETRY | 2013年 / 24卷 / 9-10期
关键词：
PROMOTED REACTIONS; DERIVATIVES; ETHER;
D O I：
10.1016/j.tetasy.2013.04.001
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
A concise chemical synthetic strategy has been developed for the synthesis of a pentasaccharide present in the O-antigen of Salmonella enterica O57 and Escherichia coli O51 strains. A sequential glycosylation strategy has been adopted for the synthesis of the target pentasaccharide. All intermediate steps are high yielding and the glycosylation steps are stereoselective. A number of recently developed methodologies have been used in the synthesis. (C) 2013 Elsevier Ltd. All rights reserved.
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页码：606 / 611
页数：6
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