Bioactive Diopside (CaMgSi2O6) as a Drug Delivery Carrier - A Review

被引：14
作者：
Saravanan, C. [1 ]
Sasikumar, S. [1 ]
机构：
[1] VIT Univ, Sch Adv Sci, Ctr Nanomat, Mat Chem Div, Vellore 632014, Tamil Nadu, India
来源：
CURRENT DRUG DELIVERY | 2012年 / 9卷 / 06期
关键词：
Diopside; Sol-gel synthesis; Microspheres; Bioactivity; Drug delivery system; IN-VITRO BIOACTIVITY; GLASS-CERAMICS; BONE-CEMENT; SINTERING BEHAVIOR; APATITE FORMATION; FORMING ABILITY; SYSTEM; MICROSPHERES; BIOMATERIALS; STABILITY;
D O I：
10.2174/156720112803529765
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The bone infections are the most divesting complications confronted by the physicians and patients. The antibiotic loaded bone cements, such as synthetic ceramics and natural ceramics were accepted for bone infections. The currently available bone cements were not accepted due to the lack of mechanical strength, porosity and quick degradation rate etc. The major aim of this review is to discuss about several different synthetic methods used to prepare the bioactive diopside (CaMgSi2O6) and its applications in ceramic drug delivery systems for controlled and targeted delivery. It has been reported from various research articles, diopside was mainly used for bone tissue regeneration, dentistry, orthopedics and enzyme delivery matrices with different formulations. Compared to other bioceramics diopside is preferable due to its biocompatibility and high mechanical strength.
引用
收藏
页码：583 / 587
页数：5
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