Use of Nitric Oxide Producer L-Arginine during Infusion Therapy of Experimental Hemorrhagic Shock

被引:2
作者
Grishina, G. V. [1 ]
Gerbut, K. A. [1 ]
Remizova, M. I. [1 ]
Selivanov, E. A. [1 ]
机构
[1] Fed Med & Biol Agcy, Russian Res Inst Hematol & Transfusiol, Dept Blood Substitutes & Components, St Petersburg, Russia
关键词
hemorrhagic shock; circulation; nitric oxide; L-arginine; RESUSCITATION;
D O I
10.1007/s10517-013-1939-1
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Experiments on rats showed that infusion of NO precursor L-arginine before bleeding enhanced their tolerance to hemorrhagic shock. When infused after blood loss as a component of saline solution, L-arginine improved effi ciency of infusion therapy for hemorrhagic shock and increased survival rate of the animals.
引用
收藏
页码:312 / 315
页数:4
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