Ceftriaxone-resistant, multidrug-resistant Neisseria gonorrhoeae with a novel mosaic penA-237.001 gene, France, June 2022

被引：16

作者：

Bercot, Beatrice ^{[1
,2
,3
]}

Camelena, Francois ^{[1
,2
,3
]}

Merimeche, Manel ^{[1
,2
,3
]}

Jacobsson, Susanne ^{[4
]}

Sbaa, Ghalia ^{[2
,3
]}

Mainardis, Mary ^{[2
,3
]}

Valin, Cyrille ^{[5
]}

Molina, Jean-Michel ^{[6
,7
]}

Bebear, Cecile ^{[8
]}

Chazelle, Emilie ^{[9
]}

Lot, Florence ^{[9
]}

Goliparian, Daniel ^{[4
]}

Unemo, Magnus ^{[4
,10
]}

机构：

[1] Univ Paris Cite, IAME, INSERM, Paris, France

[2] St Louis Hosp, AP HP, Infect Agents Dept, Paris, France

[3] French Natl Reference Ctr Bacterial STIs, Associated Lab Gonococci, Paris, France

[4] Orebro Univ, Fac Med & Hlth, Dept Lab Med, Natl Reference Lab STIs,WHO Collaborating Ctr Gon, Orebro, Sweden

[5] Biogroup, Lab Anse, Lyon, France

[6] Hop St Louis, AP HP, Lariboisiere, Dept Malad Infect & Trop, Paris, France

[7] Univ Paris Cite, UMR S976, INSERM, Paris, France

[8] Univ Bordeaux, Bordeaux Univ Hosp, USC EA 3671, Mycoplasmal & Chlamydial Infect Humans,French Nat, Bordeaux, France

[9] French Natl Publ Hlth Agcy, Sante Publ France, St Maurice, France

[10] UCL, Inst Global Hlth, London, England

来源：

EUROSURVEILLANCE | 2022年 / 27卷 / 50期

关键词：

ANTIMICROBIAL RESISTANCE; ALLELE; STRAIN;

D O I：

10.2807/1560-7917.ES.2022.27.50.2200899

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

We report a ceftriaxone-resistant, multidrug-resistant urogenital gonorrhoea case in a heterosexual woman in France, June 2022. The woman was successfully treated with azithromycin 2 g. She had unprotected sex with her regular partner, who developed urethritis following travel to Vietnam and Switzerland. Whole genome sequencing of the gonococcal isolate (F92) identified MLST ST1901, NG-STAR CC- 199, and the novel mosaic penA-237.001, which caused ceftriaxone resistance. penA-237.001 is 98.7% identical to penA-60.001, reported in various ceftriaxone-resistant strains, including the internationally spreading FC428 clone.

引用

页码：17 / 22

页数：6

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