low density lipoprotein;
cholesterol;
atherosclerosis;
history;
LOW-DENSITY LIPOPROTEINS;
HUMAN SERUM-LIPOPROTEINS;
TERMINAL AMINO-ACIDS;
HUMAN PLASMA;
INTEGRATED APPROACH;
FAT TRANSPORT;
POSTHEPARIN PLASMA;
SELECTIVE MEASUREMENT;
TRIGLYCERIDE LIPASE;
BETA-LIPOPROTEIN;
D O I:
10.1194/jlr.R069575
中图分类号:
Q5 [生物化学];
Q7 [分子生物学];
学科分类号:
071010 ;
081704 ;
摘要:
This review outlines major milestones in the first four decades of lipoprotein research beginning with their discovery nearly 90 years ago. It focuses on the contributions of some of the key investigators during this era, and findings that set the stage for widespread clinical implementation of lipoprotein testing for evaluation and management of CVD risk.