Sensors Based on Single- and Double-Layer Plasticized Membranes for the Potentiometric Determination of Mefenamic and Phenylanthranylic Acids

被引：7

作者：

Kormosh, Zh A. ^{[1
]}

Matviichuk, O. Yu ^{[1
]}

Antal, I. P. ^{[1
]}

Bazel, Ya R. ^{[2
,3
]}

机构：

[1] Lesya Ukrainka East European Natl Univ, Chem Dept, UA-43000 Lutsk, Ukraine

[2] Pavel Jozef Safarik Univ, SK-04154 Kosice, Slovakia

[3] Uzhgorod Natl Univ, UA-88000 Uzhgorod, Ukraine

来源：

JOURNAL OF ANALYTICAL CHEMISTRY | 2020年 / 75卷 / 06期

关键词：

sensors; mefenamic and phenylanthranylic acids; potentiometric determination; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; SPECTROPHOTOMETRIC DETERMINATION; VOLTAMMETRIC DETERMINATION; CARBON NANOTUBES; PARACETAMOL; EXTRACTION; PLASMA; HPLC;

D O I：

10.1134/S1061934820060131

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Sensors for the potentiometric determination of mefenamic and phenylanthranylic acids are prepared on the basis of single- and the double-layer plasticized polyvinylchloride membranes. Ion pairs of perchlorate and mefenamic and phenylanthranylic acid with basic fuchsin are synthesized for the fabrication of membranes. The composition of compounds is confirmed by spectrophotometry and IR spectrometry. Effects of different factors on the electrode characteristics are studied, the composition of the membranes is optimized. The proposed procedure for the fabrication of double-layer membranes ensures the improvement of the properties of sensors for mefenamic and phenylanthranylic acids. The developed procedures are applied to the analysis of pharmaceutical preparations.

引用

页码：820 / 828

页数：9

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