Green tea polyphenols and their potential role in health and disease

被引：179

作者：

Afzal, M. ^{[1
]}

Safer, A. M. ^{[1
]}

Menon, M. ^{[2
]}

机构：

[1] Kuwait Univ, Fac Sci, Dept Biol Sci, Kuwait, Kuwait

[2] Palmer Univ, San Jose, CA USA

来源：

INFLAMMOPHARMACOLOGY | 2015年 / 23卷 / 04期

关键词：

Green tea; Epigallocatechin gallate; Inflammation; Cancer; Fibrosis; Alzheimer; Parkinsonism; Aging; CATECHOL-O-METHYLTRANSFERASE; NF-KAPPA-B; IN-VITRO; ASCORBIC-ACID; EPIGALLOCATECHIN-3-GALLATE EGCG; (-)-EPIGALLOCATECHIN GALLATE; INFLAMMATORY RESPONSE; NATURAL POLYPHENOLS; DIETARY POLYPHENOLS; PARKINSONS-DISEASE;

D O I：

10.1007/s10787-015-0236-1

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

There is a growing body of evidence that plant polyphenols such as resveratrol, anthocyanins, catechins, and terpenes like taxol are effectively used in the treatment of chronic conditions including cancer, Alzheimer, Parkinsonism, diabetes, aging, etc. The link between oxidative stress and inflammation is well accepted. Thus, the mechanism of action of these natural products is partly believed to be through their significant antioxidant properties. The main constituent of green tea, with clinical significance, is epigallocatechin gallate (EGCG). It has been associated with antitumor, anti-Alzheimer, and anti-aging properties, improve redox status at the tissue level possibly preventing system level structural damage. This review focuses on EGCG and its potential therapeutic role in health and disease.

引用

页码：151 / 161

页数：11

共 114 条

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