Asymmetric Transfer Hydrogenation of Functionalized Acetylenic Ketones

被引：53

作者：

Fang, Zhijia ^{[1
]}

Wills, Martin ^{[1
]}

机构：

[1] Univ Warwick, Dept Chem, Coventry CV4 7AL, W Midlands, England

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2013年 / 78卷 / 17期

关键词：

ENANTIOSELECTIVE TRANSFER HYDROGENATION; DYNAMIC KINETIC RESOLUTION; ALCOHOL)-CATALYZED TRANSFER HYDROGENATION; LIGAND BIFUNCTIONAL CATALYSIS; STEREOSELECTIVE-SYNTHESIS; ALKYNYL KETONES; SELECTIVE REDUCTIONS; RUTHENIUM CATALYSTS; BETA-DIKETONES; CHIRAL SYNTHESIS;

D O I：

10.1021/jo401284c

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A systematic study of the asymmetric transfer hydrogenations of functionalized acetylenic ketones and diketones has been completed, together with a total synthesis of (S,S)-(-)-yashabushidiol B. In several cases, excellent enantioselectivities and yields were achieved.

引用

页码：8594 / 8605

页数：12

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