Mapping and Modeling Gastrointestinal Bioelectricity: From Engineering Bench to Bedside

被引：52
作者：
Cheng, L. K. [1 ,2 ]
Du, P. [1 ]
O'Grady, G. [1 ,3 ]
机构：
[1] Univ Auckland, Auckland Bioengn Inst, Auckland 1, New Zealand
[2] Vanderbilt Univ, Dept Surg, Nashville, TN 37240 USA
[3] Univ Auckland, Dept Surg, Auckland 1, New Zealand
来源：
PHYSIOLOGY | 2013年 / 28卷 / 05期
关键词：
SLOW-WAVE ACTIVITY; GASTRIC ELECTRICAL-ACTIVITY; FINITE-ELEMENT-ANALYSIS; FELINE SMALL-INTESTINE; INTERSTITIAL-CELLS; FREQUENCY GRADIENT; SPIKE PATCHES; IN-VIVO; PACEMAKER ACTIVITY; HUMAN STOMACH;
D O I：
10.1152/physiol.00022.2013
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
A key discovery in gastrointestinal motility has been the central role played by interstitial cells of Cajal (ICC) in generating electrical slow waves that coordinate contractions. Multielectrode mapping and multiscale modeling are two emerging interdisciplinary strategies now showing translational promise to investigate ICC function, electrophysiology, and contractions in the human gut.
引用
收藏
页码：310 / 317
页数：8
相关论文
共 109 条
[1]   A simple nonlinear model of electrical activity in the intestine [J].
Aliev, RR ;
Richards, W ;
Wikswo, JP .
JOURNAL OF THEORETICAL BIOLOGY, 2000, 204 (01) :21-28
[2]  
Alvarez WC, 1922, J AMER MED ASSOC, V78, P1116
[3]   Circumferential and functional re-entry of in vivo slow-wave activity in the porcine small intestine [J].
Angeli, T. R. ;
O'Grady, G. ;
Du, P. ;
Paskaranandavadivel, N. ;
Pullan, A. J. ;
Bissett, I. P. ;
Cheng, L. K. .
NEUROGASTROENTEROLOGY AND MOTILITY, 2013, 25 (05) :e304-e314
[4]   Experimental and Automated Analysis Techniques for High-resolution Electrical Mapping of Small Intestine Slow Wave Activity [J].
Angeli, Timothy R. ;
O'Grady, Gregory ;
Paskaranandavadivel, Niranchan ;
Erickson, Jonathan C. ;
Du, Peng ;
Pullan, Andrew J. ;
Bissett, Ian P. ;
Cheng, Leo K. .
JOURNAL OF NEUROGASTROENTEROLOGY AND MOTILITY, 2013, 19 (02) :179-191
[5]  
[Anonymous], NEW ADV GASTROINTEST
[6]   Gastric motor disturbances in patients with idiopathic rapid gastric emptying [J].
Bharucha, A. E. ;
Manduca, A. ;
Lake, D. S. ;
Fidler, J. ;
Edwards, P. ;
Grimm, R. C. ;
Zinsmeister, A. R. ;
Riederer, S. J. .
NEUROGASTROENTEROLOGY AND MOTILITY, 2011, 23 (07) :617-E252
[7]   Electrogastrography: A seductive promise, only partially kept [J].
Bortolotti, M .
AMERICAN JOURNAL OF GASTROENTEROLOGY, 1998, 93 (10) :1791-1794
[8]   Multiscale modelling of human gastric electric activity:: can the electrogastrogram detect functional electrical uncoupling? [J].
Buist, ML ;
Cheng, LK ;
Sanders, KM ;
Pullan, AJ .
EXPERIMENTAL PHYSIOLOGY, 2006, 91 (02) :383-390
[9]   The movements of the intestines studied means of the rontgen rays [J].
Cannon, WB .
AMERICAN JOURNAL OF PHYSIOLOGY, 1902, 6 (05) :251-277
[10]   Anatomically realistic multiscale models of normal and abnormal gastrointestinal electrical activity [J].
Cheng, Leo K. ;
Komuro, Rie ;
Austin, Travis M. ;
Buist, Martin L. ;
Pullan, Andrew J. .
WORLD JOURNAL OF GASTROENTEROLOGY, 2007, 13 (09) :1378-1383
12345678910