Microsatellite loci in the human blood fluke Schistosoma mansoni and their utility for other schistosome species

被引：44

作者：

Curtis, J ^{[1
]}

Sorensen, RE ^{[1
]}

Page, LK ^{[1
]}

Minchella, DJ ^{[1
]}

机构：

[1] Purdue Univ, Dept Biol Sci, W Lafayette, IN 47907 USA

来源：

MOLECULAR ECOLOGY NOTES | 2001年 / 1卷 / 03期

关键词：

genetic structure; microsatellites; Schistosoma; trematode;

D O I：

10.1046/j.1471-8278.2001.00053.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Blood flukes in the genus Schistosoma are important human parasites in tropical regions. Genetic heterogeneity of the parasite contributes to the observed phenotypic variation in this host-parasite interaction and may play a role in disease epidemiology. In this paper, we describe the characterization of five polymorphic microsatellite loci from the human blood fluke Schistosoma mansoni, which can now be applied in assessments of schistosome genetic diversity. The five loci revealed extensive polymorphism, as 5-8 alleles per locus were detected among five isolates (from both human patients and snail intermediate hosts) from two Brazilian villages.

引用

页码：143 / 145

页数：3

共 6 条

[1] Schistosome population genetic structure: When clumping worms is not just splitting hairs
Curtis, J
Minchella, DJ
[J]. PARASITOLOGY TODAY, 2000, 16 (02): : 68 - 71
[2] Isolation of microsatellite markers in the digenetic trematode Schistosoma mansoni from Guadeloupe island
Durand, P
Sire, C
Théron, A
[J]. MOLECULAR ECOLOGY, 2000, 9 (07) : 997 - 998
[3] Isolation and characterization of microsatellite loci in the freshwater gastropod, Biomphalaria glabrata, an intermediate host for Schistosoma mansoni
Jones, CS
Lockyer, AE
Rollinson, D
Piertney, SB
Noble, LR
[J]. MOLECULAR ECOLOGY, 1999, 8 (12) : 2149 - 2151
[4] LINCOLN SE, 1991, PRIMER VERSION 0 5 C
[5] Minchella Dennis J., 1997, P405
[6] Intraspecific variation in the rDNA its loci of 37-collar-spined echinostomes from North America: Implications for sequence-based diagnoses and phylogenetics
Sorensen, RE
Curtis, J
Minchella, DJ
[J]. JOURNAL OF PARASITOLOGY, 1998, 84 (05) : 992 - 997

← 1 →