Do we still need chemotherapy for AIDS-associated Kaposi's sarcoma?

被引：1

作者：

Dalla Pria, Alessia ^{[1
]}

Hayward, Katy ^{[1
]}

Bower, Mark ^{[1
]}

机构：

[1] Chelsea & Westminster Hosp, Natl Ctr HIV Malignancy, London SW10 9NH, England

来源：

EXPERT REVIEW OF ANTICANCER THERAPY | 2013年 / 13卷 / 02期

关键词：

AIDS; antiretrovirals; chemotherapy; HIV; Kaposi sarcoma; ACTIVE ANTIRETROVIRAL THERAPY; RECONSTITUTION INFLAMMATORY SYNDROME; PEGYLATED-LIPOSOMAL DOXORUBICIN; VASCULAR-PERMEABILITY FACTOR; PHASE-III TRIAL; IMMUNE RECONSTITUTION; DNA-SEQUENCES; MALIGNANCY CONSORTIUM; INFECTED INDIVIDUALS; PROTEASE INHIBITORS;

D O I：

10.1586/ERA.12.179

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The widespread introduction of effective combination antiretroviral therapy (cART) has had a major influence on the epidemiology and natural history of AIDS-associated Kaposi's sarcoma (AIDS-KS). cART has reduced the incidence of AIDS-KS, and it has been shown to be an effective treatment for early-stage KS. So with the widespread availability of cART, is systemic chemotherapy still required for AIDS-KS? Two indications appear to remain: advanced-stage AIDS-KS and patients who have progressive KS despite effective cART including immune reconstitution inflammatory syndrome KS.

引用

页码：203 / 209

页数：7

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