Do we still need chemotherapy for AIDS-associated Kaposi's sarcoma?

被引：1
作者：
Dalla Pria, Alessia [1 ]
Hayward, Katy [1 ]
Bower, Mark [1 ]
机构：
[1] Chelsea & Westminster Hosp, Natl Ctr HIV Malignancy, London SW10 9NH, England
来源：
EXPERT REVIEW OF ANTICANCER THERAPY | 2013年 / 13卷 / 02期
关键词：
AIDS; antiretrovirals; chemotherapy; HIV; Kaposi sarcoma; ACTIVE ANTIRETROVIRAL THERAPY; RECONSTITUTION INFLAMMATORY SYNDROME; PEGYLATED-LIPOSOMAL DOXORUBICIN; VASCULAR-PERMEABILITY FACTOR; PHASE-III TRIAL; IMMUNE RECONSTITUTION; DNA-SEQUENCES; MALIGNANCY CONSORTIUM; INFECTED INDIVIDUALS; PROTEASE INHIBITORS;
D O I：
10.1586/ERA.12.179
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The widespread introduction of effective combination antiretroviral therapy (cART) has had a major influence on the epidemiology and natural history of AIDS-associated Kaposi's sarcoma (AIDS-KS). cART has reduced the incidence of AIDS-KS, and it has been shown to be an effective treatment for early-stage KS. So with the widespread availability of cART, is systemic chemotherapy still required for AIDS-KS? Two indications appear to remain: advanced-stage AIDS-KS and patients who have progressive KS despite effective cART including immune reconstitution inflammatory syndrome KS.
引用
收藏
页码：203 / 209
页数：7
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