Viral Hepatitis and Thrombosis: A Narrative Review

被引：13

作者：

Squizzato, Alessandro ^{[1
,2
]}

Gerdes, Victor E. A. ^{[2
,3
]}

机构：

[1] Univ Insubria, Res Ctr Thromboembol Disorders & Antithrombot The, Dept Clin Med, Varese, Italy

[2] Univ Amsterdam, Acad Med Ctr, Dept Vasc Med, NL-1105 AZ Amsterdam, Netherlands

[3] Slotervaart Hosp, Dept Internal Med, Amsterdam, Netherlands

来源：

SEMINARS IN THROMBOSIS AND HEMOSTASIS | 2012年 / 38卷 / 05期

关键词：

hepatitis; thrombosis; cytomegalovirus; Epstein-Barr virus; hepatitis A; B and C virus; RETINAL VEIN OCCLUSION; CHRONIC LIVER-DISEASE; C VIRUS-INFECTION; VENOUS THROMBOSIS; ANTIPHOSPHOLIPID ANTIBODIES; ANTICARDIOLIPIN ANTIBODIES; CYTOMEGALOVIRUS-INFECTION; COAGULATION SYSTEM; INTERFERON-ALPHA; RIBAVIRIN;

D O I：

10.1055/s-0032-1305783

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Venous thromboembolism (VTE) is a multicausal disease. Among minor risk factors, acute infections in general are associated with a transient increased risk of VTE. However, acute hepatitis is usually not reported as a potential risk factor for VTE. Recent studies suggest a possible role of viral hepatitis in the development of VTE and, in particular, of portal vein thrombosis. In this narrative review, we will discuss the possible pathogenetic roles of cytomegalovirus, Epstein-Barr virus, and hepatitis A, B, and C viruses in VTE occurrence, and clinical evidence supporting this hypothesis. The hemostatic state in chronic liver disease and the role of coagulation in liver fibrosis will also be discussed.

引用

页码：530 / 534

页数：5

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