PKM2 Enters the Morpheein Academy

被引：17
作者：
Semenova, Galina [1 ]
Chernoff, Jonathan [1 ]
机构：
[1] Fox Chase Canc Ctr, Philadelphia, PA 19111 USA
来源：
MOLECULAR CELL | 2012年 / 45卷 / 05期
关键词：
PYRUVATE-KINASE M2; PROTEIN; CELLS;
D O I：
10.1016/j.molcel.2012.02.014
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In this issue of Molecular Cell, Gao et al. (2012) show that the glycolytic enzyme PKM2, in its dimeric form, possesses protein kinase activity and phosphorylates STAT3 in the nucleus, thereby driving expression of genes that promote transformation.
引用
收藏
页码：583 / 584
页数：2
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