Bronchiectasis and asthma: a dangerous liaison?

被引:36
作者
Crimi, Claudia [1 ]
Ferri, Sebastian [1 ]
Crimi, Nunzio [1 ]
机构
[1] Univ Catania, Resp Med Unit, AOU Policlin Vittorio Emanuele, Dept Clin & Expt Med, Via S Sofia 78, I-95123 Catania, Italy
关键词
asthma; bronchiectasis; infections; MUCUS HYPERSECRETION; UNCONTROLLED ASTHMA; ADULTS; INFLAMMATION; MANAGEMENT; ETIOLOGY; DISEASE; RHINOSINUSITIS; AZITHROMYCIN; CONSENSUS;
D O I
10.1097/ACI.0000000000000492
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Purpose of review To explore the latest insight of the literature on the asthma/bronchiectasis phenotype providing an updated overview about epidemiological, clinical and biological evidence linking these two conditions. Recent findings An increasing body of literature has shown that the association of asthma and bronchiectasis is a frequent phenomenon leading to a more severe disease with frequent exacerbations. The mechanisms by which the two diseases are linked are still not well established but they share several clinical and immunological features and many comorbidities. The early identification of bronchiectasis through high-definition computer tomography in patients with severe asthma is crucial in order to provide an adequate treatment for both diseases and therefore to better control symptoms, exacerbations and infections.
引用
收藏
页码:46 / 52
页数:7
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