Consolidation chemotherapy prior to hematopoietic cell transplantation for adults with acute myeloid leukemia in first remission

被引：6

作者：

Appelbaum, Frederick R. ^{[1
]}

机构：

[1] Univ Washington, Sch Med, Fred Hutchinson Canc Res Ctr, Clin Res Div,Div Med Oncol, 1100 Fairview Ave North,D5-310,POB 19024, Seattle, WA 98109 USA

来源：

BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY | 2016年 / 29卷 / 04期

关键词：

Acute myeloid leukemia; AML; Allogeneic; Autologous; Consolidation; Hematopoietic cell transplantation; HCT; Minimal residual disease; MRD; Myeloablative; Reduced intensity conditioning; RIC; ACUTE MYELOGENOUS LEUKEMIA; MINIMAL RESIDUAL DISEASE; IMPACT;

D O I：

10.1016/j.beha.2016.10.012

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Whether patients with acute myeloid leukemia (AML) should receive routine consolidation chemotherapy prior to transplant remains a significant question. Consolidation therapy may be advisable in the face of transplant delays, such as donor identification, insurance clearance, or transplant center scheduling, to prevent relapse prior to transplant. However, in cases where physicians have a choice, the question of the value of consolidation chemotherapy continues to be debated. This paper reviews the value of consolidation therapy in 4 different transplant settings. (C) 2016 Published by Elsevier Ltd.

引用

页码：365 / 371

页数：7

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