Synthesis and Biological Activity of 2-Methyl-6-chlorobenzene-sulfonylurea Derivatives

被引：4

作者：

Chen, Wei ^{[1
]}

Wei, Wei ^{[1
]}

Wu, Changchun ^{[1
]}

Li, Yuxin ^{[1
]}

Li, Yonghong ^{[1
]}

Yu, Shujing ^{[1
]}

Li, Zhengming ^{[1
]}

机构：

[1] Nankai Univ, Collaborat Innovat Ctr Chem Sci & Engn Tianjin, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China

来源：

CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2015年 / 35卷 / 07期

关键词：

sulfonylurea; chlorsulfuron; herbicidal activity; antifungal activity; HERBICIDAL ACTIVITY; ANTIFUNGAL ACTIVITY; SULFONYLUREAS; PYRIMIDINES; DESIGN;

D O I：

10.6023/cjoc201501032

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In order to study the multi-bioactivity of sulfonylurea (SU) derivatives, twelve novel 2-methyl-6-chlorobenzenesulfonylureas were designed and synthesized according to the commercialized SUs skeletons. Their structures were confirmed by H-1 NMR, C-13 NMR and FIRMS. The title compounds showed good herbicidal activity against dicotyledonous weeds by pot-culture method. For example, the herbicidal activity of 5b, 5i and 5j against Brassica napus, Amaranthus retroflexus was as effective as chlorsulfuron and monosulfuron. The in vitro antifungal test indicated that some of the target compounds exhibited good antifungal activity at the dosage of 50 mg.L-1.

引用

页码：1576 / 1581

页数：6

共 29 条

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