Synthesis and reactions of di(thiophen-2-yl)alkane diones: Cyclocondensation

被引：5
作者：
Artunc, Tekin [1 ]
Menzek, Abdullah [1 ]
机构：
[1] Ataturk Univ, Fac Sci, Dept Chem, Erzurum, Turkey
来源：
TURKISH JOURNAL OF CHEMISTRY | 2022年 / 46卷 / 05期
关键词：
Acylation; bromination; cyclocondensation; diketone; thiophene; 1ST SYNTHESIS; DERIVATIVES; THIOPHENE; BROMOPHENOLS; BROMINATION;
D O I：
10.55730/1300-0527.3446
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Known 1,6-di(thiophen-2-yl)hexane-1,6-dione (2) and novel 1,7-di(thiophen-2-yl)heptane-1,7-dione (4) were obtained from the reactions of thiophene with the corresponding diacyl chlorides. Furthermore, compounds with furan and pyrrole units in place of thiophene units in compound 2 were obtained in the same way. Bromination of 2 and 4 gave bromides regioselectively. The reaction of each of the compounds 2 and 4 in HOAc medium yielded cyclocondensation products. In total, four known and eleven novel compounds were synthesized.
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页码：1397 / +
页数：16
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