Photodynamic therapy in the treatment of circumscribed choroidal hemangioma: Current perspectives

被引:10
作者
Kumar, Ashok [1 ]
Shankar, Sandeep [1 ]
Singh, Ankita [1 ]
Mishra, Sanjay [2 ]
Kumar, Poninder [1 ]
Arora, Amit [1 ]
机构
[1] Armed Forces Med Coll, Dept Ophthalmol, Pune 411040, Maharashtra, India
[2] Army Hosp Res & Referral, Dept Ophthalmol, New Delhi 110010, India
关键词
Photodynamic therapy; Choroidal hemangioma; Half dose; Review; GAMMA-KNIFE RADIOSURGERY; TRANSPUPILLARY THERMOTHERAPY; VERTEPORFIN; EFFICACY; NEOVASCULARIZATION; PHOTOCOAGULATION; IRRADIATION; MECHANISMS; FEATURES;
D O I
10.1016/j.pdpdt.2022.103000
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Photodynamic therapy (PDT) using verteporfin Visudyne((R))(Novartis International AG, Basel, Switzerland) is widely used to treat various chorio-retinal diseases. PDT targets choroidal vascular abnormalities and induces selective occlusion of vessels. PDT was originally used in combination with full-dose verteporfin to treat neovascular age-related macular degeneration. Currently, the clinical targets of PDT have shifted to other chorioretinal conditions such as central serous chorioretinopathy, polypoidal choroidal vasculopathy and choroidal hemangioma. Clinical studies have also facilitated the optimization of treatment outcomes in choroidal hemangiomas through changes in protocols including the introduction of reduced treatment settings; such as PDT with half-dose verteporfin and half-fluence PDT. Here, we review various evolving trends in clinical application of PDT and its use for choroidal hemangiomas from a practical perspective.
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页数:6
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