Hodgkin lymphoma is a well-known clinico-pathological entity with a stable incidence among time accounting for 1200 new cases each year in France. The disease is one of the most curable cancer and occurs often in young patients with a median age at 33 years, the major clinical symptoms are lymph nodes mostly above the diaphragm (mediastinal and supra-clavicular). The diagnosis should be suggested with non-specific symptoms such as fever, night sweats, pruritus, weight-loss, lymph node, cough.. leading to prescribe routine exams like blood test with leucocyte count, erythrocyte sedimentation rate and chest Xray. Treatments always include chemotherapy and radiotherapy in localized disease and at a low dose only in involved fields. The usually good prognostic of Hodgkin lymphoma may not let us forget that there are still deaths in patients with refractory or early relapse of the disease. There is still an unmet need is these patients and the search for new drugs is essential.
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Univ Chicago Med, Dept Radiat & Cellular Oncol, Chicago, IL USAUniv Chicago Med, Dept Radiat & Cellular Oncol, Chicago, IL USA
Son, Christina H.
Chiu, Brian C. H.
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Univ Chicago, Dept Publ Hlth Sci, Chicago, IL 60637 USAUniv Chicago Med, Dept Radiat & Cellular Oncol, Chicago, IL USA
Chiu, Brian C. H.
Koshy, Matthew
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Univ Chicago Med, Dept Radiat & Cellular Oncol, Chicago, IL USA
Univ Illinois, Dept Radiat Oncol, Chicago, IL USAUniv Chicago Med, Dept Radiat & Cellular Oncol, Chicago, IL USA
机构:
Mem Sloan Kettering Canc Ctr, Dept Med, Div Hematol Oncol, Lymphoma Serv, 1275 York Ave,Box 330, New York, NY 10065 USA
Weill Cornell Med, New York, NY USAMem Sloan Kettering Canc Ctr, Dept Med, Div Hematol Oncol, Lymphoma Serv, 1275 York Ave,Box 330, New York, NY 10065 USA
机构:
Ohio State Univ, Dept Med, Div Hematol, James Canc Hosp, Columbus, OH USA
Ohio State Univ, Solove Res Inst, Columbus, OH USAOhio State Univ, Dept Med, Div Hematol, James Canc Hosp, Columbus, OH USA
Epperla, Narendranath
Hamadani, Mehdi
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Med Coll Wisconsin, Dept Med, Div Hematol & Oncol, Milwaukee, WI 53226 USA
Med Coll Wisconsin, Ctr Int Blood & Marrow Transplant Res, 9200 W Wisconsin Ave,Suite C5500, Milwaukee, WI 53226 USAOhio State Univ, Dept Med, Div Hematol, James Canc Hosp, Columbus, OH USA