VirusMINT: a viral protein interaction database

被引：153

作者：

Chatr-aryamontri, Andrew ^{[1
]}

Ceol, Arnaud ^{[1
]}

Peluso, Daniele ^{[1
,2
]}

Nardozza, Aurelio ^{[1
]}

Panni, Simona ^{[3
]}

Sacco, Francesca ^{[1
]}

Tinti, Michele ^{[1
]}

Smolyar, Alex ^{[4
,5
,6
]}

Castagnoli, Luisa ^{[1
]}

Vidal, Marc ^{[4
,5
,6
]}

Cusick, Michael E. ^{[4
,5
,6
]}

Cesareni, Gianni ^{[1
,2
]}

机构：

[1] Univ Roma Tor Vergata, Dept Biol, I-00133 Rome, Italy

[2] IRCCS Fdn Santa Lucia, I-00143 Rome, Italy

[3] Univ Calabria, Dept Cell Biol, Arcavacata Di Rende, Cs, Italy

[4] Harvard Univ, Sch Med, CCSB, Boston, MA 02115 USA

[5] Harvard Univ, Sch Med, Dept Canc Biol, Dana Farber Canc Inst, Boston, MA 02115 USA

[6] Harvard Univ, Sch Med, Dept Genet, Boston, MA 02115 USA

来源：

NUCLEIC ACIDS RESEARCH | 2009年 / 37卷

关键词：

INFORMATION; TEXT;

D O I：

10.1093/nar/gkn739

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Understanding the consequences on host physiology induced by viral infection requires complete understanding of the perturbations caused by virus proteins on the cellular protein interaction network. The VirusMINT database (http://mint.bio.uniroma2.it/virusmint/) aims at collecting all protein interactions between viral and human proteins reported in the literature. VirusMINT currently stores over 5000 interactions involving more than 490 unique viral proteins from more than 110 different viral strains. The whole data set can be easily queried through the search pages and the results can be displayed with a graphical viewer. The curation effort has focused on manuscripts reporting interactions between human proteins and proteins encoded by some of the most medically relevant viruses: papilloma viruses, human immunodeficiency virus 1, Epstein-Barr virus, hepatitis B virus, hepatitis C virus, herpes viruses and Simian virus 40.

引用

页码：D669 / D673

页数：5

共 11 条

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