Garlic (Allium sativum L.) in diabetes and its complications: Recent advances in mechanisms of action

被引：1

作者：

Jiang, Yayi ^{[1
]}

Yue, Rensong ^{[1
]}

Liu, Guojie ^{[2
]}

Liu, Jun ^{[3
]}

Peng, Bo ^{[1
]}

Yang, Maoyi ^{[1
]}

Zhao, Lianxue ^{[1
]}

Li, Zihan ^{[1
]}

机构：

[1] Hosp Chengdu Univ Tradit Chinese Med, Chengdu, Peoples R China

[2] Sichuan Univ, Sch Chem Engn, Chengdu, Peoples R China

[3] Peoples Hosp NanJiang, Bazhong, Peoples R China

来源：

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION | 2022年 / 64卷 / 16期

关键词：

Garlic extract; alliin; allicin; s-allyl cysteine; diabetes; diabetic complications; S-ALLYL CYSTEINE; FATTY LIVER-DISEASE; ANGIOTENSIN-ALDOSTERONE-SYSTEM; ENDOPLASMIC-RETICULUM STRESS; ACTIVATED PROTEIN-KINASE; GLYCATION END-PRODUCTS; BROWN ADIPOSE-TISSUE; MEDICINAL-PLANTS; OXIDATIVE STRESS; INSULIN-RESISTANCE;

D O I：

10.1080/10408398.2022.2153793

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Diabetes mellitus (DM) is a metabolic disease characterized by chronic hyperglycemia and impaired islet secretion that places a heavy burden on the global health care system due to its high incidence rate, long disease course and many complications. Fortunately, garlic (Allium sativum L.), a well-known medicinal plant and functional food without the toxicity and side effects of conventional drugs, has shown positive effects in the treatment of diabetes and its complications. With interdisciplinary development and in-depth exploration, we offer a clear and comprehensive summary of the research from the past ten years, focusing on the mechanisms and development processes of garlic in the treatment of diabetes and its complications, aiming to provide a new perspective for the treatment of diabetes and promote the efficient development of this field.

引用

页码：5290 / 5340

页数：51

共 353 条

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