Laser speckle imaging based on intensity fluctuation modulation

被引:41
作者
Zeng, Yaguang [1 ,2 ]
Wang, Mingyi [1 ]
Feng, Guangping [2 ]
Liang, Xianjun [3 ]
Yang, Guojian [1 ]
机构
[1] Beijing Normal Univ, Beijing Area Major Lab, Dept Phys & Appl Opt, Beijing 100875, Peoples R China
[2] Foshan Univ, Dept Photoelect Technol, Guangzhou 528000, Guangdong, Peoples R China
[3] Foshan Hosp Tradit Chinese Med, Guangzhou 528000, Guangdong, Peoples R China
基金
中国国家自然科学基金;
关键词
CEREBRAL-BLOOD-FLOW; IMAGES; CAMERA; TIME;
D O I
10.1364/OL.38.001313
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We present a method, intensity fluctuation modulation (IFM), to obtain a full-field laser speckle microvessel image. Different from laser speckle contrast analysis, IFM imaging is insensitive to flow velocity and can be used to reconstruct microvessel images with higher spatial resolution and SNR. An in vivo animal experiment on a mouse pinna is conducted to demonstrate that IFM imaging is capable of achieving laser speckle microangiography. (C) 2013 Optical Society of America
引用
收藏
页码:1313 / 1315
页数:3
相关论文
共 17 条
[1]   Frequency-domain wide-field laser Doppler in vivo imaging [J].
Atlan, M. ;
Gross, M. ;
Forget, B. C. ;
Vitalis, T. ;
Rancillac, A. ;
Dunn, A. K. .
OPTICS LETTERS, 2006, 31 (18) :2762-2764
[2]   Laser doppler imaging, revisited [J].
Atlan, M. ;
Gross, M. .
REVIEW OF SCIENTIFIC INSTRUMENTS, 2006, 77 (11)
[3]   Clear coherent imaging in turbid microfluidics by multiple holographic acquisitions [J].
Bianco, Vittorio ;
Paturzo, Melania ;
Finizio, Andrea ;
Balduzzi, Donatella ;
Puglisi, Roberto ;
Galli, Andrea ;
Ferraro, Pietro .
OPTICS LETTERS, 2012, 37 (20) :4212-4214
[4]   QUASI REAL-TIME DIGITAL VERSION OF SINGLE-EXPOSURE SPECKLE PHOTOGRAPHY FOR FULL-FIELD MONITORING OF VELOCITY OR FLOW-FIELDS [J].
BRIERS, JD ;
WEBSTER, S .
OPTICS COMMUNICATIONS, 1995, 116 (1-3) :36-42
[5]   Temporal statistical analysis of laser speckle images and its application to retinal blood-flow imaging [J].
Cheng, Haiying ;
Yan, Yumei ;
Duong, Timothy Q. .
OPTICS EXPRESS, 2008, 16 (14) :10214-10219
[6]   Efficient characterization of regional mesenteric blood flow by use of laser speckle imaging [J].
Cheng, HY ;
Luo, QM ;
Wang, Z ;
Gong, H ;
Chen, SB ;
Liang, WX ;
Zeng, SQ .
APPLIED OPTICS, 2003, 42 (28) :5759-5764
[7]   Laser speckle imaging of blood flow in microcirculation [J].
Cheng, HY ;
Luo, QM ;
Liu, Q ;
Lu, QA ;
Gong, H ;
Zeng, SQ .
PHYSICS IN MEDICINE AND BIOLOGY, 2004, 49 (07) :1347-1357
[8]   Laser speckle imaging for monitoring blood flow dynamics in the in vivo rodent dorsal skin fold model [J].
Choi, B ;
Kang, NM ;
Nelson, JS .
MICROVASCULAR RESEARCH, 2004, 68 (02) :143-146
[9]   Twente Optical Perfusion Camera: system overview and performance for video rate laser Doppler perfusion imaging [J].
Draijer, Matthijs ;
Hondebrink, Erwin ;
van Leeuwen, Ton ;
Steenbergen, Wiendelt .
OPTICS EXPRESS, 2009, 17 (05) :3211-3225
[10]   Dynamic imaging of cerebral blood flow using laser speckle [J].
Dunn, AK ;
Bolay, T ;
Moskowitz, MA ;
Boas, DA .
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2001, 21 (03) :195-201