Recent Developments in Nanomedicines for Management of Various Health Issues Via Metabolism and Physico-Chemical Properties

被引：5

作者：

Rasool, Mahmood ^{[1
]}

Naseer, Muhammad Imran ^{[1
]}

Malik, Arif ^{[2
]}

Manan, Abdul ^{[2
]}

Ullah, Ikram ^{[3
]}

Bin Abid, Noman ^{[3
]}

Kim, Myeong Ok

Qazi, Mahmood Husain ^{[4
]}

Kamal, Mohammad Amjad ^{[5
,6
]}

Bibi, Fehmida ^{[5
]}

机构：

[1] King Abdulaziz Univ, Ctr Excellence Genom Med Res, Jeddah 21589, Saudi Arabia

[2] Univ Lahore, Inst Mol Biol & Biotechnol, Lahore, Pakistan

[3] Gyeongsang Natl Univ, Coll Nat Sci, Div Life Sci, Jinju 660701, South Korea

[4] Univ Lahore, Ctr Res Mol Med CriMM, Lahore, Pakistan

[5] King Abdulaziz Univ, King Fahd Med Res Ctr, Jeddah 21589, Saudi Arabia

[6] Enzymoic, Hebersham, NSW 2770, Australia

来源：

CURRENT DRUG METABOLISM | 2015年 / 16卷 / 05期

关键词：

Cancer; gene therapy; liposomes; nanomedicines; neurodegenerative disorders; quantum dots; silver and gold nanoparticles; PEGYLATED LIPOSOMAL DOXORUBICIN; MODIFIED SILICA NANOPARTICLES; SILVER NANOPARTICLES; CANCER-CELLS; IN-VITRO; COMPOSITE NANOFIBERS; THERAPEUTIC-EFFICACY; POLYETHYLENE-GLYCOL; GOLD NANOPARTICLES; PANCREATIC-CANCER;

D O I：

10.2174/1389200215666141125121211

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

During the last decade the nanotechnologists began research on applications of nanomaterials for medicine and therapeutics. Various nanoparticles (nanomedicines) are being used worldwide for the diagnosis and management in a number of disorders including cancer and neurodegenerative disorders. The successful non-viral gene therapy is now possible with the advancements in nanotechnology. Mostly nanoparticles are divided into two main classes: organic and inorganic nanoparticles. Diverse features of nanomedicines with surface modification help to make them biocompatible with addition of varying polymer that facilitates targeted delivery of drug and its controlled release into the cells, tissues and organs. Liposomes, quantum dots, silver and gold nanoparticles are the most common examples of nanomedicines.

引用

页码：389 / 396

页数：8

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